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Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase

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Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase
Identifiers
EC no.2.7.8.36
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Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase (EC 2.7.8.36, PglC) is an enzyme with systematic name UDP-N,N'-diacetylbacillosamine:tritrans,heptacis-undecaprenyl-phosphate N,N'-diacetylbacillosamine transferase.[1] This enzyme catalyses the following chemical reaction

UDP-N,N'-diacetylbacillosamine + tritrans,heptacis-undecaprenyl phosphate UMP + N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol

This enzyme is isolated from Campylobacter jejuni.

References

  1. ^ Glover KJ, Weerapana E, Chen MM, Imperiali B (April 2006). "Direct biochemical evidence for the utilization of UDP-bacillosamine by PglC, an essential glycosyl-1-phosphate transferase in the Campylobacter jejuni N-linked glycosylation pathway". Biochemistry. 45 (16): 5343–50. doi:10.1021/bi0602056. PMID 16618123.

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