Respirovirus
| Respirovirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Monjiviricetes |
| Order: | Mononegavirales |
| Family: | Paramyxoviridae |
| Subfamily: | Orthoparamyxovirinae |
| Genus: | Respirovirus |
| Species | |
| Synonyms[1] | |
| |
Respirovirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae[2]. Rodents and human serve as natural hosts. There are currently seven species in this genus including the type species Murine respirovirus.[3] Diseases associated with this genus include: croup and other acute febrile respiratory tract infections.[4]
Structure
Respirovirions are enveloped, with spherical geometries. The diameter is around 150 nm. Respirovirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.[3][4]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Respirovirus | Spherical | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. Translation takes place by leaky scanning, and ribosomal shunting. The virus exits the host cell by budding. Rodents and human serve as the natural host. Transmission routes are respiratory.[3][4]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Respirovirus | Rodents; humans | None | Glycoprotein | Budding | Cytoplasm | Cytoplasm | Aerosols |
References
- ^ Pringle, C. R. (1998). "Virus taxonomy-San Diego 1998" (PDF). Archives of Virology. 143 (7): 1449–59. doi:10.1007/s007050050389. PMID 9742051.
- ^ Rima, B; Balkema-Buschmann, A; Dundon, WG; Duprex, P; Easton, A; Fouchier, R; Kurath, G; Lamb, R; Lee, B; Rota, P; Wang, L; ICTV Report Consortium (December 2019). "ICTV Virus Taxonomy Profile: Paramyxoviridae". The Journal of General Virology. 100 (12): 1593–1594. doi:10.1099/jgv.0.001328. PMID 31609197.
- ^ a b c "Virus Taxonomy: 2019 Release". talk.ictvonline.org. International Committee on Taxonomy of Viruses. Retrieved 8 May 2020.
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
External links