Adrian is an unincorporated community in Rock Creek Township, Hancock County, Illinois, United States. Adrian no longer has a Post Office, but is served by Dallas City. It hosts a grain elevator, Chemagro, and several houses. A former Disciples of Christ Church stands at the west end of the community, but is no longer active. The former one-room school at the east end of the community is now a farm machine shed.
Adrian was laid out in the 1870s, taking its name from Adrian, Michigan. A post office has been in operation at Adrian since 1870.
Adrian is located at 40°31′15″N 91°10′02″W / 40.52083°N 91.16722°W at an elevation of 699 feet.