Ewan Birney
Ewan Birney | |
---|---|
![]() Ewan Birney in 2014, portrait courtesy of the Royal Society | |
Born | December 1972 (age 51)[33][34][35] |
Alma mater | |
Known for | |
Spouse |
Barley Birney (née Laycock)
(m. 2003) |
Children | Two[34] |
Awards |
|
Scientific career | |
Fields | |
Institutions | |
Thesis | Sequence alignment in bioinformatics (2000) |
Doctoral advisor | Richard Durbin[9] |
Doctoral students | |
Other notable students | Mikhail Spivakov (postdoc)[25][26][27] |
Website |
John Frederick William Birney, known as Ewan, (born 1972)[34][35] FRS[5] FMedSci[7] is joint Director with Rolf Apweiler of the European Bioinformatics Institute (EBI),[43][44][45][46] part of the European Molecular Biology Laboratory (EMBL) in Hinxton, Cambridgeshire. He is also an Associate Faculty member at the Wellcome Trust Sanger Institute[47] and an Honorary Professor of Bioinformatics at the University of Cambridge.[48] Birney has made significant contributions to the analysis of genomes. Through his development of innovative bioinformatics and computational biology tools, researchers around the world are able to predict and annotate regions of interest in DNA with speed and confidence.[1]
Education
Birney was educated at Eton College as an Oppidan Scholar where he studied GCE Advanced Levels in Maths, Biology, Chemistry and Art.[34][49] Before going to university, Birney completed a gap year internship at Cold Spring Harbor Laboratory supervised by James Watson[35][29] and Adrian Krainer.[29][50][51] He acted as a bookmaker to the genomics community, taking bets on estimates of the total number of genes (and so-called "junk DNA"[52]) in the human genome.[29][53][54]
Birney completed his Bachelor of Arts degree in Biochemistry at Balliol College, Oxford in 1996[34][35][55] followed by a PhD at the Wellcome Trust Sanger Institute, supervised by Richard Durbin[9] as postgraduate student of St John's College, Cambridge.[56][57] During his university education[when?] he completed an internship in financial services in the City of London for the Swiss Bank Corporation.[29][49]
Research
Birney is one of the founders of the Ensembl genome browser and other databases, and has played a key role in many large-scale genomics projects, notably the sequencing of the Human Genome in 2000 and the analysis of genome function in the ENCODE project.[54][58] He has played a role in annotating the genome sequences of the human,[59] mouse,[60] chicken[61] and several other organisms. His research group focuses on genomic algorithms and inter-individual differences in human and other animal species.[42][43][46][52][62][63][64][65][66][67]
Birney is known for his role in the ENCODE consortium.[8][54][68][69][70][71][72] Prior to the ENCODE project, Birney has been involved in the creation of a number of widely used bioinformatics and computational biology tools, either directly (PairWise,[37] GeneWise,[38] GenomeWise,[39]), or in collaboration with students and postdocs, e.g. Exonerate[40] (with Guy Slater), Enredo (Javier Herrero[73]), Pecan (Benedict Paten[19]), the Velvet assembler (Daniel Zerbino[74] ) and CRAM (Markus Hsi-Yang Fritz,[12] Rasko Leinonen[75] and Vadim Zalunin). Birney has also contributed to several other projects including the Pfam[76] database, InterPro,[77] BioPerl,[78][79] and HMMER[80] and Ensembl[81] toolkits.
As of 2015[update] Birney's research group focuses on genomic algorithms and studying inter individual differences, in both human and other species. He has supervised several PhD students and postdocs that have worked in his laboratory.[10][12][13][17][19][20][21][24][82] This research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC), Medical Research Council (MRC)[83] the Wellcome Trust and the European Union.[84] Birney is also a consultant to Oxford Nanopore Technologies[85] and on the scientific advisory board of The Genome Analysis Centre (TGAC) in Norwich.[86][87]
Awards and honours
Birney has won several awards: In 2003, he gave the inaugural Francis Crick Lecture at the Royal Society:
The inaugural Francis Crick Lecture was awarded to Birney, for his leading role in establishing international standards for software used in genome informatics, and in making research data and software openly available to the research community. The lecture, entitled 'Being human: what our genome tells us' took place at the Royal Society on 4 December 2003.[1]
In 2005, Birney was awarded the Overton Prize by the International Society for Computational Biology (ISCB):
Dr. Ewan Birney of the European Molecular Biology Laboratory (EMBL) European Bioinformatics Institute (EBI), was awarded the 2005 Overton Prize in honour of his advocacy of open source bioinformatics, and his generous contributions to the BioPerl community. Perhaps even more important to biology is his leadership of the Ensembl genome annotation project, providing rapid and accurate computational annotations for eukaryotic genomes."[2]
In 2005 Birney was awarded the Benjamin Franklin Award in Bioinformatics:
As expressed by his nominators, Birney has been a significant force in Open Source in Bioinformatics and science. He has been a strong advocate for making genome information freely available to all. His work co-leading the Ensembl project has made high-quality genome annotation available freely over the web, preventing a class system of labs which can and cannot afford to pay subscription fees to proprietary data. The project has worked hard to make the data available in a variety of ways to make the data accessible and easily available for mining. The Ensembl project has been open-source from the outset, enabling researchers and corporations alike to reuse and extend the software system. Birney has been an advocate of open science as well. Along with Sean Eddy, he criticised journal decisions to allow papers to be published without releasing the genome sequence data at the same time. He is also the author of the freely available Wise package of tools, which are important parts of genome annotation pipelines. He serves as a co-leader of the open-source bioinformatics toolkit Bioperl and also co-founded and currently serves as president of the Open Bioinformatics foundation, an organisation that support the development of several bioinformatics toolkits.[88]
Birney was elected a Fellow of the Royal Society (FRS) in 2014.[31][1] His certificate of election and candidature reads
Ewan has grown to be a force in genomics due to his innovation in genome analysis, both algorithmic and integrative analyses. He wrote the first error tolerant, splice aware protein alignment program, used in the human and subsequent genome analysis; he co-authored one of the first and most widely used short read assemblers. In terms of data integration, Ewan has led the analysis in many genomic consortia, in particular ENCODE, leading the integration of many genomic assays; for example making robust predictions of enhancers, promoters, and their integration with disease associated regions. He also co-developed many widely used bioinformatics resources.[5]
In 2015, Birney was elected a Fellow of the Academy of Medical Sciences (FMedSci). His citation on election reads:
Associate Director of the European Bioinformatics Institute, Dr Ewan Birney has been a prominent leader in genomics internationally for many years and led the ENCODE project. He is a polymath who has drawn from diverse fields, such as speech recognition, computer science and human genetics, to develop world-leading research programmes in population and comparative genomics. His influence on genomics has been profound, and he has contributed new tools and concepts that have been far ahead of their time. His central position in genomics/bioinformatics in Europe and indeed the world gives him a deep understanding of the impact of genomics technologies on future healthcare and health economics.[7]
In 2014, Birney was awarded an Honorary Doctor of Science (DSc) degree from Brunel University London in recognition of his service to science.[89] In 2002, Birney was named as one of the MIT Technology Review TR100 top 100 innovators in the world under the age of 35:[90] Birney was also awarded EMBO Membership[3] in 2012.[4]
Personal life
Birney is married to Barley Birney (née Laycock)[42] with two children.[34] He appeared on a special Christmas edition of University Challenge in 2014 representing Balliol College, Oxford with Charlotte Higgins and Alan Beith.[91]
References
- ^ a b c d Anon (2014). "Dr Ewan Birney FMedSci FRS". London: Royal Society. Archived from the original on 17 November 2015. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 25 September 2015)
- ^ a b "ISCB Newsletter 8-2 Dr. Ewan Birney Named as the 2005 Overton Prize Winner!". Archived from the original on 28 February 2012.
- ^ a b "The EMBO Pocket Directory" (PDF). European Molecular Biology Organization. Archived from the original on 16 March 2015.
- ^ a b "EMBO MEMBER: Ewan Birney". Heidelberg: European Molecular Biology Organization.
- ^ a b c "Certificate of election EC/2014/06: Ewan Birney FRS". London: Royal Society. Archived from the original on 22 December 2015.
- ^ https://www.ebi.ac.uk/about/news/press-releases/ewan-birney-FRS
- ^ a b c "Dr Ewan Birney FRS FMedSci". London: Academy of Medical Sciences. Archived from the original on 6 July 2015.
- ^ a b Ewan Birney publications indexed by Google Scholar
- ^ a b Birney, Ewan (2000). Sequence alignment in bioinformatics (PhD thesis). University of Cambridge. OCLC 894597337.
- ^ a b Ettwiller, Laurence Michele (2004). Computational Investigations into cis-Regulation in Eukaryotes (PhD thesis). University of Cambridge. OCLC 890156758.
- ^ Ettwiller, L. M.; Rung, J.; Birney, E. (2003). "Discovering Novel cis-Regulatory Motifs Using Functional Networks". Genome Research. 13 (5): 883–895. doi:10.1101/gr.866403. PMC 430934. PMID 12727907.
- ^ a b c Fritz, Markus (2011). Exploiting high throughput DNA sequencing data for genomic analysis (PDF) (PhD thesis). University of Cambridge. OCLC 890152397.
- ^ a b Hoffman, Michael (2008). Quantifying evolution and natural selection in vertebrate noncoding sequence (PhD thesis). University of Cambridge. OCLC 885435476.
- ^ Hoffman, M. M.; Birney, E. (2006). "Estimating the Neutral Rate of Nucleotide Substitution Using Introns". Molecular Biology and Evolution. 24 (2): 522–531. doi:10.1093/molbev/msl179. PMID 17122369.
- ^ Kölling, Nils (2016). Quantitative genetics of gene expression during fruit fly development (PhD thesis). University of Cambridge. doi:10.17863/CAM.26.
- ^ "Nils Kölling - Statistical Bioinformatician/Geneticist".
- ^ a b Meynert, Alison Maria (2009). Function and evolution of regulatory elements in vertebrates (PhD thesis). University of Cambridge. OCLC 890148982.
- ^ Meynert, A.; Birney, E. (2006). "Picking Pyknons out of the Human Genome". Cell. 125 (5): 836–838. doi:10.1016/j.cell.2006.05.019. PMID 16751093.
- ^ a b c Paten, Benedict John (2006). Large-scale multiple alignment and transcriptionally associated pattern discovery in vertebrate genomes (PhD thesis). University of Cambridge. OCLC 890155216.
- ^ a b Ruklisa, Dace (2015). Large Scale Genomic Association Studies in Fruit Fly and Human (PhD thesis). University of Cambridge. OCLC 890151540.
- ^ a b Timmer, Sander Willem (2015). Understanding the epigenome using system genetics (PhD thesis). University of Cambridge.
- ^ "Sander Timmer – PhD candidate in Biological Sciences". Archived from the original on 2 July 2013.
- ^ Gibson, Greg; Ding, Zhihao; Ni, Yunyun; Timmer, Sander W.; Lee, Bum-Kyu; Battenhouse, Anna; Louzada, Sandra; Yang, Fengtang; Dunham, Ian; Crawford, Gregory E.; Lieb, Jason D.; Durbin, Richard; Iyer, Vishwanath R.; Birney, Ewan (2014). "Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association". PLoS Genetics. 10 (11): e1004798. doi:10.1371/journal.pgen.1004798. ISSN 1553-7404.
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: CS1 maint: unflagged free DOI (link) - ^ a b Zerbino, Daniel Robert (2009). Genome assembly and comparison (PhD thesis). University of Cambridge. OCLC 890153795.
- ^ Spivakov, M.; Akhtar, J.; Kheradpour, P.; Beal, K.; Girardot, C.; Koscielny, G.; Herrero, J.; Kellis, M.; Furlong, E. E.; Birney, E. (2012). "Analysis of variation at transcription factor binding sites in Drosophila and humans". Genome Biology. 13 (9): R49. doi:10.1186/gb-2012-13-9-r49. PMC 3491393. PMID 22950968.
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: CS1 maint: unflagged free DOI (link) - ^ "Ewan's Blog; bioinformatician at large: ENCODE: My own thoughts". Archived from the original on 12 February 2013.
- ^ Junion, G.; Spivakov, M.; Girardot, C.; Braun, M.; Gustafson, E. H.; Birney, E.; Furlong, E. E. M. (2012). "A Transcription Factor Collective Defines Cardiac Cell Fate and Reflects Lineage History". Cell. 148 (3): 473–486. doi:10.1016/j.cell.2012.01.030. PMID 22304916.
- ^ a b Birney, Ewan (2014). "Ewan Birney's homepage". European Bioinformatics Institute. Archived from the original on 27 December 2014.
- ^ a b c d e "The Life Scientific, Ewan Birney interviewed by Jim Al-Khalili". 11 June 2013., BBC Radio 4
- ^ "John Frederick William Birney". Oxford University Gazette. 124 (4305). Oxford University Press. 4 November 1993. Archived from the original on 16 June 2015.
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: Cite has empty unknown parameter:|1=
(help) - ^ a b "Fellowship of the Royal Society 1660-2015". London: Royal Society. Archived from the original on 15 July 2015.
- ^ Ewan Birney's ORCID 0000-0001-8314-8497
- ^ "John Frederick William BIRNEY, Eagle Genomics Limited". London: Companies House. Archived from the original on 25 April 2016.
- ^ a b c d e f g h BIRNEY. "BIRNEY, Dr Ewan". Who's Who. Vol. 2015 (online Oxford University Press ed.). A & C Black.
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: Unknown parameter|othernames=
ignored (help) (Subscription or UK public library membership required.) (subscription required) - ^ a b c d Hopkin, Karen (June 2005). "Bring Me Your Genomes: The Ewan Birney Story". The Scientist. 19 (11): 60. Archived from the original on 10 June 2011. Retrieved 10 June 2011.
- ^ Hubbard, T.; Barker, D.; Birney, E.; Cameron, G.; Chen, Y.; Clark, L.; Cox, T.; Cuff, J.; Curwen, V.; Down, T.; Durbin, R.; Eyras, E.; Gilbert, J.; Hammond, M.; Huminiecki, L.; Kasprzyk, A.; Lehvaslaiho, H.; Lijnzaad, P.; Melsopp, C.; Mongin, E.; Pettett, R.; Pocock, M.; Potter, S.; Rust, A.; Schmidt, E.; Searle, S.; Slater, G.; Smith, J.; Spooner, W.; Stabenau, A. (2002). "The Ensembl genome database project". Nucleic Acids Research. 30 (1): 38–41. doi:10.1093/nar/30.1.38. PMC 99161. PMID 11752248.
- ^ a b Birney, E.; Thompson, J.; Gibson, T. (1996). "PairWise and SearchWise: Finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames". Nucleic Acids Research. 24 (14): 2730–2739. doi:10.1093/nar/24.14.2730. PMC 145991. PMID 8759004.
- ^ a b Birney, E.; Durbin, R. (2000). "Using GeneWise in the Drosophila annotation experiment". Genome Research. 10 (4): 547–548. doi:10.1101/gr.10.4.547. PMC 310858. PMID 10779496.
- ^ a b Birney, E.; Clamp, M.; Durbin, R. (2004). "GeneWise and Genomewise". Genome Research. 14 (5): 988–995. doi:10.1101/gr.1865504. PMC 479130. PMID 15123596.
- ^ a b Slater, G.; Birney, E. (2005). "Automated generation of heuristics for biological sequence comparison". BMC Bioinformatics. 6: 31. doi:10.1186/1471-2105-6-31. PMC 553969. PMID 15713233.
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: CS1 maint: unflagged free DOI (link) - ^ ENCODE Project Consortium; Birney E; Stamatoyannopoulos JA; Dutta A; Guigó R; Gingeras TR; Margulies EH; Weng Z; Snyder M; Dermitzakis ET; et al. (2007). "Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project". Nature. 447 (7146): 799–816. Bibcode:2007Natur.447..799B. doi:10.1038/nature05874. PMC 2212820. PMID 17571346.
- ^ a b c Pennisi, Elizabeth (2012). "Profile of Ewan Birney: Genomics' Big Talker". Science. 337 (6099): 1167–1169. doi:10.1126/science.337.6099.1167. PMID 22955814.
- ^ a b Ewan Birney publications from Europe PubMed Central
- ^ Ewan Birney on X
- ^ Parkhill, J; Birney, E; Kersey, P (2010). "Genomic information infrastructure after the deluge". Genome Biology. 11 (7): 402. doi:10.1186/gb-2010-11-7-402. PMC 2926780. PMID 20670392.
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: CS1 maint: unflagged free DOI (link) - ^ a b Kellis, M; Wold, B; Snyder, M. P.; Bernstein, B. E.; Kundaje, A; Marinov, G. K.; Ward, L. D.; Birney, E; Crawford, G. E.; Dekker, J; Dunham, I; Elnitski, L. L.; Farnham, P. J.; Feingold, E. A.; Gerstein, M; Giddings, M. C.; Gilbert, D. M.; Gingeras, T. R.; Green, E. D.; Guigo, R; Hubbard, T; Kent, J; Lieb, J. D.; Myers, R. M.; Pazin, M. J.; Ren, B; Stamatoyannopoulos, J. A.; Weng, Z; White, K. P.; Hardison, R. C. (2014). "Defining functional DNA elements in the human genome". Proceedings of the National Academy of Sciences. 111 (17): 6131–6138. Bibcode:2014PNAS..111.6131K. doi:10.1073/pnas.1318948111. PMC 4035993. PMID 24753594.
- ^ "Sanger Faculty". Wellcome Trust Sanger Institute. Archived from the original on 16 March 2015.
- ^ "Honorary Professors". Cambridge University Reporter. CXLV (5). University of Cambridge. 12 December 2014. Archived from the original on 15 March 2015.
- ^ a b "Dr Ewan Birney FRS". thescientific23.com. Archived from the original on 6 July 2015.
- ^ Birney, E.; Kumar, S.; Krainer, A. (1992). "A putative homolog of U2AF65 in S. Cerevisiae". Nucleic Acids Research. 20 (17): 4663. doi:10.1093/nar/20.17.4663. PMC 334203. PMID 1408772.
- ^ "Ewan Birney: 'There is a mistaken view that scientists are unemotional people | Science | The Observer 10th February 2013". The Guardian. London. 10 February 2013.
- ^ a b Hall, Stephen S. (2012). "Journey to the genetic interior. What was once known as junk DNA turns out to hold hidden treasures, says computational biologist Ewan Birney". Scientific American. 307 (4): 80–82, 84. doi:10.1038/scientificamerican1012-80. PMID 23029896.
- ^ Pertea, M.; Salzberg, S. L. (2010). "Between a chicken and a grape: Estimating the number of human genes". Genome Biology. 11 (5): 206. doi:10.1186/gb-2010-11-5-206. PMC 2898077. PMID 20441615.
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: CS1 maint: unflagged free DOI (link) - ^ a b c Graur, D.; Zheng, Y.; Price, N.; Azevedo, R. B. R.; Zufall, R. A.; Elhaik, E. (2013). "On the Immortality of Television Sets: "Function" in the Human Genome According to the Evolution-Free Gospel of ENCODE". Genome Biology and Evolution. 5 (3): 578–590. doi:10.1093/gbe/evt028. PMC 3622293. PMID 23431001.
- ^ "The age of the genome, Ewan Birney in Floreat Domus". Archived from the original on 28 February 2012.Balliol College newspaper
- ^ "EBI's Ewan Birney: Quest for the Genomic Dragons". Science Watch Newsletter Interview
- ^ Smaglik, Paul (2012). "Turning point: Ewan Birney". Nature. 482 (7383): 123–728. doi:10.1038/nj7383-123a.
- ^ "ENCODE: Encyclopedia of DNA Elements" on YouTube
- ^ Lander, E. S.; Linton, M.; Birren, B.; Nusbaum, C.; Zody, C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; Fitzhugh, W.; Funke, R.; Gage, D.; Harris, K.; Heaford, A.; Howland, J.; Kann, L.; Lehoczky, J.; Levine, R.; McEwan, P.; McKernan, K.; Meldrim, J.; Mesirov, J. P.; Miranda, C.; Morris, W.; Naylor, J.; Raymond, C.; Rosetti, M.; Santos, R.; Sheridan, A.; Sougnez, C. (February 2001). "Initial sequencing and analysis of the human genome". Nature. 409 (6822): 860–921. Bibcode:2001Natur.409..860L. doi:10.1038/35057062. ISSN 0028-0836. PMID 11237011.
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: Unknown parameter|displayauthors=
ignored (|display-authors=
suggested) (help) - ^ Chinwalla, A. T.; Waterston, L. L.; Lindblad-Toh, K. D.; Birney, G. A.; Rogers, L. A.; Abril, R. S.; Agarwal, T. A.; Agarwala, L. W.; Ainscough, E. R.; Alexandersson, J. D.; An, T. L.; Antonarakis, W. E.; Attwood, J. O.; Baertsch, M. N.; Bailey, K. H.; Barlow, C. S.; Beck, T. C.; Berry, B.; Birren, J.; Bloom, E.; Bork, R. H.; Botcherby, M. C.; Bray, R. K.; Brent, S. P.; Brown, P.; Brown, E.; Bult, B.; Burton, T.; Butler, D. G.; Campbell, J. (2002). "Initial sequencing and comparative analysis of the mouse genome". Nature. 420 (6915): 520–562. Bibcode:2002Natur.420..520W. doi:10.1038/nature01262. PMID 12466850.
- ^ Eyras, E.; Reymond, A.; Castelo, R.; Bye, J. M.; Camara, F.; Flicek, P.; Huckle, E. J.; Parra, G.; Shteynberg, D. D.; Wyss, C.; Rogers, J.; Antonarakis, S. E.; Birney, E.; Guigo, R.; Brent, M. R. (2005). "Gene finding in the chicken genome". BMC Bioinformatics. 6: 131. doi:10.1186/1471-2105-6-131. PMC 1174864. PMID 15924626.
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: CS1 maint: unflagged free DOI (link) - ^ "Churchill College: Biographies: Ewan Birney". Archived from the original on 28 February 2012.
- ^ Goldman, N.; Bertone, P.; Chen, S.; Dessimoz, C.; Leproust, E. M.; Sipos, B.; Birney, E. (2013). "Towards practical, high-capacity, low-maintenance information storage in synthesized DNA". Nature. 494 (7435): 77–80. Bibcode:2013Natur.494...77G. doi:10.1038/nature11875. PMC 3672958. PMID 23354052.
- ^ "An Interview with Ewan Birney: Keynote Speaker at O'Reilly's Bioinformatics Technology Conference". O'Reilly Media. Archived from the original on 27 May 2015.
- ^ Ewan Birney's publications indexed by the Scopus bibliographic database. (subscription required)
- ^ Jupp, S; Malone, J; Bolleman, J; Brandizi, M; Davies, M; Garcia, L; Gaulton, A; Gehant, S; Laibe, C; Redaschi, N; Wimalaratne, S. M.; Martin, M; Le Novère, N; Parkinson, H; Birney, E; Jenkinson, A. M. (2014). "The EBI RDF platform: Linked open data for the life sciences". Bioinformatics. 30 (9): 1338–9. doi:10.1093/bioinformatics/btt765. PMC 3998127. PMID 24413672.
- ^ Marti-Solano, M; Birney, E; Bril, A; Della Pasqua, O; Kitano, H; Mons, B; Xenarios, I; Sanz, F (2014). "Integrative knowledge management to enhance pharmaceutical R&D". Nature Reviews Drug Discovery. 13 (4): 239–40. doi:10.1038/nrd4290. PMID 24687050.
- ^ Kellis, M.; Wold, B.; Snyder, M. P.; Bernstein, B. E.; Kundaje, A.; Marinov, G. K.; Ward, L. D.; Birney, E.; Crawford, G. E.; Dekker, J.; Dunham, I.; Elnitski, L. L.; Farnham, P. J.; Feingold, E. A.; Gerstein, M.; Giddings, M. C.; Gilbert, D. M.; Gingeras, T. R.; Green, E. D.; Guigo, R.; Hubbard, T.; Kent, J.; Lieb, J. D.; Myers, R. M.; Pazin, M. J.; Ren, B.; Stamatoyannopoulos, J.; Weng, Z.; White, K. P.; Hardison, R. C. (2014). "Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease". Proceedings of the National Academy of Sciences. 111 (33): E3366–E3366. doi:10.1073/pnas.1410434111. ISSN 0027-8424.
- ^ Birney, E. (2012). "The making of ENCODE: Lessons for big-data projects". Nature. 489 (7414): 49–51. Bibcode:2012Natur.489...49B. doi:10.1038/489049a. PMID 22955613.
- ^ Dunham, I.; Bernstein, A.; Birney, S. F.; Dunham, P. J.; Green, C. A.; Gunter, F.; Snyder, C. B.; Frietze, S.; Harrow, J.; Kaul, R.; Khatun, J.; Lajoie, B. R.; Landt, S. G.; Lee, B. K.; Pauli, F.; Rosenbloom, K. R.; Sabo, P.; Safi, A.; Sanyal, A.; Shoresh, N.; Simon, J. M.; Song, L.; Trinklein, N. D.; Altshuler, R. C.; Birney, E.; Brown, J. B.; Cheng, C.; Djebali, S.; Dong, X.; Dunham, I. (2012). "An integrated encyclopedia of DNA elements in the human genome". Nature. 489 (7414): 57–74. Bibcode:2012Natur.489...57T. doi:10.1038/nature11247. PMC 3439153. PMID 22955616.
- ^ ENCODE Project Consortium (2011). Becker PB (ed.). "A User's Guide to the Encyclopedia of DNA Elements (ENCODE)". PLOS Biology. 9 (4): e1001046. doi:10.1371/journal.pbio.1001046. PMC 3079585. PMID 21526222.
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: CS1 maint: unflagged free DOI (link) - ^ Ewan Birney at DBLP Bibliography Server
- ^ Paten, B.; Herrero, J.; Beal, K.; Fitzgerald, S.; Birney, E. (2008). "Enredo and Pecan: Genome-wide mammalian consistency-based multiple alignment with paralogs". Genome Research. 18 (11): 1814–1828. doi:10.1101/gr.076554.108. PMC 2577869. PMID 18849524.
- ^ Zerbino, D. R.; Birney, E. (2008). "Velvet: Algorithms for de novo short read assembly using de Bruijn graphs". Genome Research. 18 (5): 821–829. doi:10.1101/gr.074492.107. ISSN 1088-9051.
- ^ Leinonen, R.; Akhtar, R.; Birney, E.; Bonfield, J.; Bower, L.; Corbett, M.; Cheng, Y.; Demiralp, F.; Faruque, N.; Goodgame, N.; Gibson, R.; Hoad, G.; Hunter, C.; Jang, M.; Leonard, S.; Lin, Q.; Lopez, R.; Maguire, M.; McWilliam, H.; Plaister, S.; Radhakrishnan, R.; Sobhany, S.; Slater, G.; Ten Hoopen, P.; Valentin, F.; Vaughan, R.; Zalunin, V.; Zerbino, D.; Cochrane, G. (2009). "Improvements to services at the European Nucleotide Archive". Nucleic Acids Research. 38 (Database issue): D39–D45. doi:10.1093/nar/gkp998. PMC 2808951. PMID 19906712.
- ^ Bateman, A.; Birney, E.; Cerruti, L.; Durbin, R.; Etwiller, L.; Eddy, S.; Griffiths-Jones, S.; Howe, K.; Marshall, M.; Sonnhammer, E. L. (2002). "The Pfam protein families database". Nucleic Acids Research. 30 (1): 276–280. doi:10.1093/nar/30.1.276. PMC 99071. PMID 11752314.
- ^ Apweiler, R.; Attwood, T. K.; Bairoch, A.; Bateman, A.; Birney, E.; Biswas, M.; Bucher, P.; Cerutti, L.; Corpet, F.; Croning, M. D.; Durbin, R.; Falquet, L.; Fleischmann, W.; Gouzy, J.; Hermjakob, H.; Hulo, N.; Jonassen, I.; Kahn, D.; Kanapin, A.; Karavidopoulou, Y.; Lopez, R.; Marx, B.; Mulder, N. J.; Oinn, T. M.; Pagni, M.; Servant, F.; Sigrist, C. J.; Zdobnov, E. M. (2001). "The InterPro database, an integrated documentation resource for protein families, domains and functional sites". Nucleic Acids Research. 29 (1): 37–40. doi:10.1093/nar/29.1.37. PMC 29841. PMID 11125043.
- ^ Stajich, J. E.; Block, D.; Boulez, K.; Brenner, S.; Chervitz, S.; Dagdigian, C.; Fuellen, G.; Gilbert, J.; Korf, I.; Lapp, H.; Lehväslaiho, H.; Matsalla, C.; Mungall, C. J.; Osborne, B. I.; Pocock, M. R.; Schattner, P.; Senger, M.; Stein, L. D.; Stupka, E.; Wilkinson, M. D.; Birney, E. (2002). "The BioPerl Toolkit: Perl Modules for the Life Sciences". Genome Research. 12 (10): 1611–1618. doi:10.1101/gr.361602. PMC 187536. PMID 12368254.
- ^ "Ewan Birney - BioPerl". Archived from the original on 12 February 2013.
- ^ Bateman, A.; Birney, E.; Durbin, R.; Eddy, S.; Finn, R.; Sonnhammer, E. (1999). "Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins". Nucleic Acids Research. 27 (1): 260–262. doi:10.1093/nar/27.1.260. PMC 148151. PMID 9847196.
- ^ Flicek, P.; Ahmed, I.; Amode, M. R.; Barrell, D.; Beal, K.; Brent, S.; Carvalho-Silva, D.; Clapham, P.; Coates, G.; Fairley, S.; Fitzgerald, S.; Gil, L.; Garcia-Giron, C.; Gordon, L.; Hourlier, T.; Hunt, S.; Juettemann, T.; Kahari, A. K.; Keenan, S.; Komorowska, M.; Kulesha, E.; Longden, I.; Maurel, T.; McLaren, W. M.; Muffato, M.; Nag, R.; Overduin, B.; Pignatelli, M.; Pritchard, B.; Pritchard, E. (2012). "Ensembl 2013". Nucleic Acids Research. 41 (D1): D48–D55. doi:10.1093/nar/gks1236. PMC 3531136. PMID 23203987.
- ^ "EMBL International PhD Programme - completed theses | EBI Training". Archived from the original on 12 February 2013.
- ^ "UK Government Research grants awarded to Ewan Birney". Swindon: Research Councils UK. Archived from the original on 4 June 2015.
- ^ "Google Tech Talk 2012-07-12: Human Genetics and Genomics: The Science for the 21st Century by Ewan Birney" on YouTube
- ^ Cookson, Clive (17 February 2012). "Oxford Nanopore unveils mini-DNA reader". Financial Times. London. Retrieved 20 October 2014.
- ^ "TGAC new Scientific Advisory Board: a multidisciplinary set of key experts". TGAC Norwich UK.
- ^ Big Data of Pharma – Ewan Birney, Big Data in Biomedicine conference, Stanford University School of Medicine
- ^ Bioinformatics Press release Ewan Birney wins the 2005 Benjamin Franklin Award in Bioinformatics
- ^ "In recognition of his outstanding service to science, Dr Ewan Birney is awarded the honorary degree of Doctor of Science". Brunel University London. Archived from the original on 21 April 2015.
- ^ "2002 Young Innovators Under 35: Ewan Birney, 29". Technology Review. 2002. Archived from the original on 28 February 2012.
- ^ Anonymous (2014). "University Challenge, Christmas 2014 Episode 5 of 10". BBC.
- Use dmy dates from April 2012
- Living people
- Members of the European Molecular Biology Organization
- People educated at Eton College
- Alumni of Balliol College, Oxford
- Alumni of St John's College, Cambridge
- British biochemists
- Bioinformaticians
- Overton Prize winners
- Fellows of Churchill College, Cambridge
- Wellcome Trust
- 1972 births
- Fellows of the Royal Society
- Fellows of the International Society for Computational Biology
- Fellows of the Academy of Medical Sciences
- Human Genome Project scientists