FCGRT

From Wikipedia, the free encyclopedia
Jump to: navigation, search
FCGRT
Protein FCGRT PDB 1exu.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases FCGRT, FCRN, alpha-chain, Fc fragment of IgG receptor and transporter
External IDs MGI: 103017 HomoloGene: 3030 GeneCards: FCGRT
RNA expression pattern
PBB GE FCGRT 218831 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136019
NM_004107

NM_010189

RefSeq (protein)

NP_001129491
NP_004098

NP_034319.2
NP_034319

Location (UCSC) Chr 19: 49.51 – 49.53 Mb Chr 7: 45.09 – 45.1 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene.[3][4][5]

Interactions[edit]

FCGRT has been shown to interact with Human serum albumin.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Story CM, Mikulska JE, Simister NE (December 1994). "A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus". J. Exp. Med. 180 (6): 2377–81. doi:10.1084/jem.180.6.2377. PMC 2191771Freely accessible. PMID 7964511. 
  4. ^ Kandil E, Egashira M, Miyoshi O, Niikawa N, Ishibashi T, Kasahara M, Miyosi O (July 1996). "The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3". Cytogenet. Cell Genet. 73 (1-2): 97–8. doi:10.1159/000134316. PMID 8646894. 
  5. ^ "Entrez Gene: FCGRT Fc fragment of IgG, receptor, transporter, alpha". 
  6. ^ Chaudhury C, Mehnaz S, Robinson JM, Hayton WL, Pearl DK, Roopenian DC, Anderson CL (February 2003). "The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan". J. Exp. Med. 197 (3): 315–22. doi:10.1084/jem.20021829. PMC 2193842Freely accessible. PMID 12566415. 

Further reading[edit]