Fc receptor-like molecule

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Fc receptor-like molecules (FCRLs) are a class of proteins that resemble Fc receptors. They have been characterized in a number of species, including humans and mice. They are preferentially expressed by B lymphocytes. Unlike the classical Fc receptors, there is no strong evidence that suggests that FCRLs bind to the Fc portion of antibodies. Their function is unknown. [1]


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  1. ^ Davis, RS (2007). "Fc Receptor-Like Molecules". Annual Review of Immunology 25 (1): 525–560. doi:10.1146/annurev.immunol.25.022106.141541. PMID 17201682. 
  2. ^ Santiago T, Kulemzin SV, Reshetnikova ES, et al. (December 2010). "FCRLA is a resident endoplasmic reticulum protein that associates with intracellular Igs, IgM, IgG and IgA". Int Immunol 23 (1): 43–53. doi:10.1093/intimm/dxq456. PMC 3003704. PMID 21149418.