Phasmaviridae

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Phasmaviridae
Virus classification e
(unranked): Virus
Realm: Riboviria
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Phasmaviridae
Genera[1]

Phasmaviridae is a family of viruses with negative stranded RNA genomes associated with insect hosts. They are a member of the order Bunyavirales.[1] Phasmaviruses were first discovered in phantom midges of the genus Chaoborus in 2014[2].

Taxonomy[edit]

Five genera are currently recognized in this family.[1]

Ferak feravirus[edit]

Ferak feravirus, a member of the genus Feravirus, has been isolated in cell culture. The virion is enveloped and spherical with a diameter of 80–120 nanometers. The genome has three segments L (6.8 kilobases), M (4.2 kilobases) and S (1.5 kilobases). It encodes five proteins—the polymerase on the L segment, the p12G and the Gc-Gn protein on the M segment and the N and p12 proteins in the S segment.[3]

A Gn–Gc glycoprotein dimer binds to the cell receptor. The virus is endocytosed and escapes into the cytoplasm where it replicates. It is released from the cell by budding.[3]

References[edit]

  1. ^ a b c Virus Taxonomy: 2018 Release, International Committee on Taxonomy of Viruses, retrieved 2018-12-05
  2. ^ Ballinger, M. J.; Bruenn, J. A.; Hay, J.; Czechowski, D.; Taylor, D. J. (2014-08-15). "Discovery and Evolution of Bunyavirids in Arctic Phantom Midges and Ancient Bunyavirid-Like Sequences in Insect Genomes". Journal of Virology. 88 (16): 8783–8794. doi:10.1128/JVI.00531-14. ISSN 0022-538X. PMC 4136290. PMID 24850747.
  3. ^ a b Marklewitz M, Zirkel F, Kurth A, Drosten C, Junglen S (2015) Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family. Proc Natl Acad Sci USA 112(24):7536–7541. doi: 10.1073/pnas.1502036112

External links[edit]