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Phasmaviridae

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Phasmaviridae
Virus classification
Group:
Group V ((−)ssRNA)
Order:
Family:
Feraviridae
Genera

Orthoferavirus

Feraviridae is a family of viruses with negative stranded RNA genomes. They are a member of the order Bunyavirales.

Taxonomy

There is one genus currently recognised in this family—Orthoferavirus.

Structure

The type species of this family—Ferak virus—has been isolated in cell culture.[1]

The virion is enveloped and spherical with a diameter of 80–120 nanometers.

The genome has three segments L (6.8 kilbases), M (4.2 kilobases) and S (1.5 kilobases). It encodes five proteins—the polymerase on the L segment, the p12G and the Gc-Gn protein on the M segment and the N and p12 proteins in the S segmement.

Life cycle

A Gn–Gc glycoprotein dimer binds to the cell receptor. The virus is endocytosed and escapes into the cytoplasm where it replicates. It is released from the cell by budding.

References

  1. ^ Marklewitz M, Zirkel F, Kurth A, Drosten C, Junglen S (2015) Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family. Proc Natl Acad Sci USA 112(24):7536–7541. doi: 10.1073/pnas.1502036112