L-threonine dehydrogenase
L-Threonine dehydrogenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.103 | ||||||||
CAS no. | 9067-99-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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L-Threonine dehydrogenase | |||||||
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Identifiers | |||||||
Symbol | TDH | ||||||
NCBI gene | 157739 | ||||||
HGNC | 15547 | ||||||
RefSeq | NM_152566 | ||||||
UniProt | Q8IZJ6 | ||||||
Other data | |||||||
EC number | 1.1.1.103 | ||||||
Locus | Chr. 8 p23.1 | ||||||
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L-Threonine dehydrogenase is an enzyme that facilitates the catabolism of threonine. It catalyses its conversion to glycine via 2-amino-3-ketobutyrate with concomitant reduction of NAD+.
References
- Epperly BR, Dekker EE (April 1991). "L-threonine dehydrogenase from Escherichia coli. Identification of an active site cysteine residue and metal ion studies". The Journal of Biological Chemistry. 266 (10): 6086–92. PMID 2007567.
- Edgar AJ (October 2002). "The human L-threonine 3-dehydrogenase gene is an expressed pseudogene". BMC Genetics. 3: 18. doi:10.1186/1471-2156-3-18. PMC 131051. PMID 12361482.
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