|Systematic (IUPAC) name|
|CAS Registry Number|
|Molecular mass||366.458 g/mol|
Liafensine (BMS-820836) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) which was under development by Bristol-Myers Squibb for the treatment of major depressive disorder. Though it demonstrated comparable effectiveness to escitalopram and duloxetine in phase II clinical trials, development was terminated in 2013 because liafensine failed to show superior effectiveness relative to these drugs, a decision which was made likely based on its increased capacity for side effects as well as theoretical potential for abuse.
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