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RTI-353 structure.png
Systematic (IUPAC) name
methyl (1R,2S,3S,5S)-3-(4-ethyl-3-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
PubChem CID: 9801045
Chemical data
Formula C17H22INO2
Molecular mass 399.266 g/mol
 YesY (what is this?)  (verify)

RTI-353 is a phenyltropane derived drug which acts as an SSRI.[1][2] Tamagnan et al. also made some phenyltropanes with high activity and selectivity for the SERT (pM affinity).


  1. ^ Navarro HA, Xu H, Zhong D, Blough BE, Ross WP, Kuhar MJ, Carroll FI. [(125)I]3beta-(4-ethyl-3-iodophenyl)nortropane-2beta-carboxylic acid methyl ester ([(125)I]EINT): a potent and selective radioligand for the brain serotonin transporter. Synapse. 2001 Sep 1;41(3):241-7. PMID 11418937
  2. ^ [1]