6-Nitroquipazine

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6-Nitroquipazine
6-nitroquinpazine.svg
Systematic (IUPAC) name
6-nitro-2-piperazin-1-yl-quinoline
Legal status
Legal status
  • Uncontrolled
Identifiers
CAS Number 77372-73-7 N
ATC code none
PubChem CID 5012
ChemSpider 4837 YesY
ChEMBL CHEMBL41140 YesY
Chemical data
Formula C13H14N4O2
Molar mass 258.28 g/mol
 NYesY (what is this?)  (verify)

6-Nitroquipazine (DU-24,565) is a potent and selective serotonin reuptake inhibitor used in scientific research.[1][2]

6-nitroquipazine has been found to inhibit melanogenesis in-vitro,[3] suggesting that it can be used for skin whitening.

See also[edit]

References[edit]

  1. ^ Vaatstra WJ, Deiman-Van Aalst WM, Eigeman L (March 1981). "Du 24565, a quipazine derivative, a potent selective serotonin uptake inhibitor". European Journal of Pharmacology. 70 (2): 195–202. doi:10.1016/0014-2999(81)90214-4. PMID 6973481. 
  2. ^ Classen K, Göthert M, Schlicker E (June 1984). "Effects of DU 24565 (6-nitroquipazine) on serotoninergic and noradrenergic neurones of the rat brain and comparison with the effects of quipazine". Naunyn-Schmiedeberg's Archives of Pharmacology. 326 (3): 198–202. doi:10.1007/bf00505318. PMID 6206407. 
  3. ^ Max, McEwan; Persons, Peter G. (1987). "Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor" (PDF). J. Invest. Dermatol. 89 (1). doi:10.1111/1523-1747.ep12580425. PMID 3110297.  No-cost access but non-free license.