6-Nitroquipazine

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6-Nitroquipazine
6-nitroquinpazine.svg
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
Formula C13H14N4O2
Molar mass 258.28 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

6-Nitroquipazine (DU-24,565) is a potent and selective serotonin reuptake inhibitor used in scientific research.[1][2]

6-nitroquipazine has been found to inhibit melanogenesis in-vitro,[3] suggesting that it can be used for skin whitening.

See also[edit]

References[edit]

  1. ^ Vaatstra WJ, Deiman-Van Aalst WM, Eigeman L (March 1981). "Du 24565, a quipazine derivative, a potent selective serotonin uptake inhibitor". European Journal of Pharmacology. 70 (2): 195–202. PMID 6973481. doi:10.1016/0014-2999(81)90214-4. 
  2. ^ Classen K, Göthert M, Schlicker E (June 1984). "Effects of DU 24565 (6-nitroquipazine) on serotoninergic and noradrenergic neurones of the rat brain and comparison with the effects of quipazine". Naunyn-Schmiedeberg's Archives of Pharmacology. 326 (3): 198–202. PMID 6206407. doi:10.1007/bf00505318. 
  3. ^ Max, McEwan; Persons, Peter G. (1987). "Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor" (PDF). J. Invest. Dermatol. 89 (1). PMID 3110297. doi:10.1111/1523-1747.ep12580425.  No-cost access but non-free license.