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May-Britt Moser

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May-Britt Moser
File:E-MB-Moser-20100819.gif
May-Britt and Edvard Moser in 2010
Born (1963-01-04) 4 January 1963 (age 61)
Fosnavåg, Norway
NationalityNorwegian
Known forGrid cells, Neurons
SpouseEdvard Moser
AwardsNobel Prize in Physiology or Medicine (2014)
Scientific career
FieldsNeuroscience
InstitutionsKavli Institute for Systems Neuroscience and Centre for the Biology of Memory

May-Britt Moser (born 4 January 1963) is a Norwegian psychologist, neuroscientist and founding director of the Kavli Institute for Systems Neuroscience and Centre for the Biology of Memory at the Norwegian University of Science and Technology (NTNU) in Trondheim, Norway.[1]

Moser and her husband Edvard have pioneered research on the brain's mechanism for representing space. Edvard and May-Britt Moser were appointed associate professors in psychology and neuroscience at NTNU in 1996, less than one year after their Ph.D defenses. They established The Centre for the Biology of Memory (CBM) in 2002 and the Kavli Institute, the 15th in the world and the 4th in neuroscience, in 2007. May-Britt shared the Nobel prize in Physiology or Medicine in 2014, together with her husband Edvard and John O'Keefe.[2]

The research institutes

The scientific goal of the Kavli Institute for Systems Neuroscience and Centre for the Biology of Memory is to advance our understanding of neural circuits and systems. By focusing on spatial representation and memory, the investigators hope to uncover general principles of neural network computation in the mammalian cortex.[3]

The Kavli Institute, supported by the Kavli Foundation, coexists with the Centre for the Biology of Memory (CBM), but the scope of the Institute is broader and more long-term. CBM is part of the Centre of Excellence scheme of the Research Council of Norway. The KI/CBM is also funded by the EU's Seventh Research Framework Programme (FP7) and an Advanced Investigator Grant from the European Research Council (ERC).[4]

Career

May-Britt Moser has a degree in Psychology from the University of Oslo in 1990. She thereafter obtained her Ph.D. in Neurophysiology from the University of Oslo in 1995,[5] under the supervision of professor Per Andersen. Moser went on to undertake postdoctoral training with Richard Morris at the Centre for Neuroscience, University of Edinburgh from 1994 to 1996, and was a visiting postdoctoral fellow at the laboratory of John O'Keefe at the University College, London.

Moser returned to Norway in 1996 to be appointed Associate Professor in Biological Psychology at the Norwegian University of Science and Technology (NTNU) in Trondheim. She was promoted to Full professor of Neuroscience at NTNU in 2000. Moser is also the founding co-director of the NTNU Centre for the Biology of Memory (2002) and the Kavli Institute for Systems Neuroscience (2007). Further, she was awarded one half of the Nobel Prize in Physiology or Medicine 2014, along with her husband Edvard Moser, with the other half going to John O'Keefe.[6] She is a also a member of the Royal Norwegian Society of Sciences and Letters,[7] Norwegian Academy of Science and Letters,[8] and the Norwegian Academy of Technological Sciences.[9]

Honours

Other

  • Moser was appointed by the European Research Council as a member of one of the evaluation panels for ERC startup grants for the period 2007-09.
  • In 2013 Moser received the Madame Beyer "Best female boss" award, in recognition of Moser's superb leadership, scientific achievements and her high ethical standards, as well as her consistent focus on team work and community spirit.[citation needed]

Selected publications

  • Brun, V.H., Otnæss, M.K., Molden, S., Steffenach, H.-A., Witter, M.P., Moser, M.-B., Moser, E.I. (2002). Place cells and place representation maintained by direct entorhinal-hippocampal circuitry. Science, 296, 2089-2284.
  • Fyhn, M., Molden, S., Witter, M.P., Moser, E.I. and Moser, M.-B. (2004). Spatial representation in the entorhinal cortex.Science, 305, 1258-1264.
  • Leutgeb, S., Leutgeb, J.K., Treves, A., Moser, M.-B. and Moser, E.I. (2004). Distinct ensemble codes in hippocampal areas CA3 and CA1. Science, 305, 1295-1298.
  • Leutgeb, S., Leutgeb, J.K., Barnes, C.A., Moser, E.I., McNaughton, B.L., and Moser, M.-B (2005). Independent codes for spatial and episodic memory in the hippocampus. Science, 309, 619-623.
  • Hafting, T., Fyhn, M., Molden, S., Moser, M.-B., and Moser, E.I. (2005). Microstructure of a spatial map in the entorhinal cortex.Nature, 436, 801-806.
  • Sargolini, F., Fyhn, M., Hafting, T., McNaughton, B.L., Witter, M.P., Moser, M.-B., and Moser, E.I. (2006). Conjunctive representation of position, direction and velocity in entorhinal cortex. Science, 312, 754-758.
  • Leutgeb, J.K., Leutgeb, S., Moser, M.-B., and Moser, E.I. (2007). Pattern separation in dentate gyrus and CA3 of the hippocampus. Science, 315, 961-966.
  • Fyhn, M., Hafting, T., Treves, A., Moser, M.-B. and Moser, E.I. (2007). Hippocampal remapping and grid realignment in entorhinal cortex. Nature, 446, 190-194.
  • Hafting, T., Fyhn, M., Bonnevie, T., Moser, M.-B. and Moser, E.I. (2008). Hippocampus-independent phase precession in entorhinal grid cells. Nature 453, 1248-1252.
  • Kjelstrup, K.B., Solstad, T., Brun, V.H., Hafting, T., Leutgeb, S., Witter, M.P., Moser, E.I. and Moser, M.-B. (2008). Finite scales of spatial representation in the hippocampus. Science 321, 140-143.
  • Solstad, T., Boccara, C.N., Kropff, E., Moser, M.-B. and Moser, E.I. (2008). Representation of geometric borders in the entorhinal cortex. Science, 322, 1865-1868.
  • Moser, E.I., Moser, M-B. (2011). Crystals of the brain. EMBO Mol. Med. 3, 1-4.
  • Moser, E.I., Moser, M-B. (2011). Seeing into the future. Nature, 469, 303-4
  • Jezek, K., Henriksen, EJ., Treves, A., Moser, E.I. and Moser, M-B. (2011). Theta-paced flickering between place-cell maps in the hippocampus. Nature, 478, 246-249.
  • Giocomo, LM., Moser, E.I., Moser, M-B. (2011) Grid cells use HCN1 channels for spatial scaling. Cell, 147, 1159-1170.

References

  1. ^ [http://www.ntnu.no/english NTNU official website[; accessed 7 October 2014.
  2. ^ May-Britt Moser profile, Academia-Net.org; accessed 7 October 2014.
  3. ^ Kavli Institute for Systems Neuroscience website; accessed 7 October 2014.
  4. ^ Kavli Foundation website; accessed 7 October 2014.
  5. ^ Moser, M-B. (1995). Structural correlates of spatial learning in the hippocampus of adult rats. Thesis for the degree of Ph.D, University of Oslo (Defended, 9 December 1995)
  6. ^ a b May-Britt Moser profile: The 2014 Nobel Prize in Physiology or Medicine, nobelprize.org; accessed 7 October 2014.
  7. ^ "Gruppe IV Generell biologi" (in Norwegian). Royal Norwegian Society of Sciences and Letters. Retrieved 6 October 2014.
  8. ^ "Gruppe 7: Medisinske fag" (in Norwegian). Norwegian Academy of Science and Letters. Retrieved 28 October 2009.
  9. ^ "Medlemmer: MOSER, May Britt" (in Norwegian). Norwegian Academy of Technological Sciences. Retrieved 11 May 2013.
  10. ^ The Anders Jahre Senior Medical Prize
  11. ^ 13th Perl-UNC Neuroscience Prize Recipients UNC Neuroscience Center. Retrieved 23 September 2013
  12. ^ Louisa Gross Horwitz Prize 2013
  13. ^ Award Ceremonies Amphilsoc.org. Retrieved 21 March 2014
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