Molybdopterin adenylyltransferase
| Molybdopterin adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.75 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Molybdopterin adenylyltransferase (EC 2.7.7.75, MogA, Cnx1) is an enzyme with systematic name ATP:molybdopterin adenylyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + molybdopterin diphosphate + adenylyl-molybdopterin
This enzyme catalyses the activation of molybdopterin for molybdenum insertion.
References
- ^ Nichols, J.D.; Rajagopalan, K.V. (2005). "In vitro molybdenum ligation to molybdopterin using purified components". J. Biol. Chem. 280 (9): 7817–7822. doi:10.1074/jbc.M413783200. PMID 15632135.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Kuper, J.; Palmer, T.; Mendel, R.R.; Schwarz, G. (2000). "Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization". Proc. Natl. Acad. Sci. USA. 97 (12): 6475–6480. doi:10.1073/pnas.110568497. PMC 18627. PMID 10823911.
- ^ Llamas, A.; Mendel, R.R.; Schwarz, G. (2004). "Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion". J. Biol. Chem. 279 (53): 55241–55246. doi:10.1074/jbc.M409862200. PMID 15504727.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
External links
- Molybdopterin+adenylyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)