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Pantoate kinase

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Pantoate kinase
Identifiers
EC no.2.7.1.169
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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NCBIproteins

Pantoate kinase (EC 2.7.1.169, PoK, TK2141 protein) is an enzyme with systematic name ATP:(R)-pantoate 4-phosphotransferase.[1] This enzyme catalyses the following chemical reaction

ATP + (R)-pantoate ADP + (R)-4-phosphopantoate

The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is done during biosynthesis of 4'-phosphopantetheine,.

References

  1. ^ Yokooji, Y., Tomita, H., Atomi, H. and Imanaka, T. (2009). "Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea". J. Biol. Chem. 284: 28137–28145. doi:10.1074/jbc.m109.009696. PMID 19666462.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)