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Yoshinori Ohsumi

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Yoshinori Ohsumi
Yoshinori Ōsumi
Born (1945-02-09) February 9, 1945 (age 79)
Fukuoka, Japan
NationalityJapanese
Alma materUniversity of Tokyo
Known forAutophagy
AwardsNobel Prize in Physiology or Medicine (2016)
Scientific career
FieldsCell biologist
InstitutionsTokyo Institute of Technology
Websitewww.ohsumilab.aro.iri.titech.ac.jp

Yoshinori Ohsumi (大隅 良典, Ōsumi Yoshinori) (born February 9, 1945) is a Japanese cell biologist specializing in autophagy. Ohsumi is a professor in Tokyo Institute of Technology's Frontier Research Center.[1] He received the Kyoto Prize for Basic Science in 2012,[2] and the 2016 Nobel Prize in Physiology or Medicine for his discoveries of mechanisms for autophagy.[3]

Biography

Ohsumi was born on February 9, 1945 in Fukuoka, Japan. He received a B.Sci. in 1967 and a D.Sci. in 1974, both from the University of Tokyo. In 1974–77 he was a postdoctoral fellow at the Rockefeller University in New York City.[1]

He returned to The University of Tokyo in 1977 as a Research Associate; he was appointed Lecturer there in 1986, and promoted to Associate Professor in 1988. In 1996 he moved to the National Institute for Basic Biology in Okazaki City, Japan. where he was appointed Professor. From 2004 to 2009 he was also professor at the Graduate University for Advanced Studies in Hayama, Japan. In 2009 he transitioned to a three-way appointment as Emeritus Professor at the National Institute for Basic Biology and at the Graduate University for Advanced Studies, and a Professorship at Advanced Research Organization, Integrated Research Institute, Tokyo Institute of Technology. Even after his retirement on 2014, he still continue to serve as Professor at Institute of Innovative Research, Tokyo Institute of Technology until now. Currently, he is head of Cell Biology Research Unit, Institute of Innovative Research, Tokyo Institute of Technology.

In 2016 he was awarded the Nobel Prize in Physiology or Medicine for discovering the mechanisms for autophagy.

Awards

Publications

  • Tsukada, M; Ohsumi, Y (25 October 1993). "Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae". FEBS letters. 333 (1–2): 169–74. PMID 8224160.
  • Mizushima, N; Noda, T; Yoshimori, T; Tanaka, Y; Ishii, T; George, MD; Klionsky, DJ; Ohsumi, M; Ohsumi, Y (24 September 1998). "A protein conjugation system essential for autophagy". Nature. 395 (6700): 395–8. PMID 9759731.
  • Ichimura, Y; Kirisako, T; Takao, T; Satomi, Y; Shimonishi, Y; Ishihara, N; Mizushima, N; Tanida, I; Kominami, E; Ohsumi, M; Noda, T; Ohsumi, Y (23 November 2000). "A ubiquitin-like system mediates protein lipidation". Nature. 408 (6811): 488–92. PMID 11100732.
  • Ohsumi, Y (March 2001). "Molecular dissection of autophagy: two ubiquitin-like systems". Nature reviews. Molecular cell biology. 2 (3): 211–6. PMID 11265251.
  • Kuma, A; Hatano, M; Matsui, M; Yamamoto, A; Nakaya, H; Yoshimori, T; Ohsumi, Y; Tokuhisa, T; Mizushima, N (23 December 2004). "The role of autophagy during the early neonatal starvation period". Nature. 432 (7020): 1032–6. PMID 15525940.
  • Hanada, T; Noda, NN; Satomi, Y; Ichimura, Y; Fujioka, Y; Takao, T; Inagaki, F; Ohsumi, Y (28 December 2007). "The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy". The Journal of biological chemistry. 282 (52): 37298–302. PMID 17986448.

References

  1. ^ a b Yoshinori Ohsumi's ORCID 0000-0003-2384-2166
  2. ^ Lawrence Biemiller, "Kyoto Prize Is Awarded to 3 Scholars" The Chronicle of Higher Education Nov. 10, 2012 [1]
  3. ^ "The Nobel Prize in Physiology or Medicine 2016". The Nobel Foundation. 3 October 2016. Retrieved 3 October 2016.
  4. ^ "Yoshinori Ohsumi". Kyoto Prize. Retrieved 3 October 2016.
  5. ^ "Yoshinori Ohsumi wins Nobel prize in medicine for work on autophagy". The Guardian. Retrieved 3 October 2016.

See also

Wikimedia Commons has media related to Yoshinori Ōsumi.
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