Tesetaxel: Difference between revisions

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'''Tesetaxel''' ('''DJ-927''') is a drug being investigated for [[chemotherapy]] of various types of cancer, including [[breast cancer]],<ref>{{ClinicalTrialsGov|NCT01609127|Tesetaxel Every 3 Weeks vs Weekly vs Capecitabine as 1st-line Therapy for Locally Advanced or Metastatic Breast Cancer}}</ref> [[gastric cancer]],<ref>{{ClinicalTrialsGov|NCT01348009|Tesetaxel Plus Capecitabine and Cisplatin in Advanced Gastric Cancer}}</ref> and other solid tumours.<ref>{{pmid|21547572}}</ref>
'''Tesetaxel''' ('''DJ-927''') is a drug being investigated for [[chemotherapy]] of various types of cancer, including [[breast cancer]],<ref>{{ClinicalTrialsGov|NCT01609127|Tesetaxel Every 3 Weeks vs Weekly vs Capecitabine as 1st-line Therapy for Locally Advanced or Metastatic Breast Cancer}}</ref> [[gastric cancer]],<ref>{{ClinicalTrialsGov|NCT01348009|Tesetaxel Plus Capecitabine and Cisplatin in Advanced Gastric Cancer}}</ref> and other solid tumours.<ref>{{cite pmid|21547572}}</ref>


==References==
==References==

Revision as of 22:47, 12 July 2014

Tesetaxel
Clinical data
ATC code
  • none
Legal status
Legal status
  • Investigational
Identifiers
  • (2aS,2bR,3S,4S,6S,8aR,10S,11aS,11bR,13aR)-2a-(acetyloxy)-6-{[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-3-(3-fluoropyridin-2-yl)-2-hydroxypropanoyl]oxy}-10-[(dimethylamino)methyl]-4-hydroxy-7,11b,14,14-tetramethyl-2a,2b,3,4,5,6,8a,11a,11b,12,13,13a-dodecahydro-2H-4,8-methano[1,3]dioxolo[3,4]cyclodeca[1,2-d][1]benzoxet-3-yl benzoate
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC46H60FN3O13
Molar mass881.98 g/mol g·mol−1
3D model (JSmol)
  • CC1=C2[C@@H]3[C@H]([C@@]4(CC[C@@H]5[C@]([C@H]4[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C6=C(C=CC=N6)F)NC(=O)OC(C)(C)C)O)O)OC(=O)C7=CC=CC=C7)(CO5)OC(=O)C)C)O[C@@H](O3)CN(C)C
  • InChI=1S/C46H60FN3O13/c1-24-28(58-40(54)34(52)33(32-27(47)17-14-20-48-32)49-41(55)63-42(3,4)5)21-46(56)38(61-39(53)26-15-12-11-13-16-26)36-44(8,19-18-29-45(36,23-57-29)62-25(2)51)37-35(31(24)43(46,6)7)59-30(60-37)22-50(9)10/h11-17,20,28-30,33-38,52,56H,18-19,21-23H2,1-10H3,(H,49,55)/t28-,29+,30+,33-,34+,35+,36-,37+,38-,44+,45-,46+/m0/s1 ☒N
  • Key:MODVSQKJJIBWPZ-VLLPJHQWSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Tesetaxel (DJ-927) is a drug being investigated for chemotherapy of various types of cancer, including breast cancer,[1] gastric cancer,[2] and other solid tumours.[3]

References

  1. ^ Clinical trial number NCT01609127 for "Tesetaxel Every 3 Weeks vs Weekly vs Capecitabine as 1st-line Therapy for Locally Advanced or Metastatic Breast Cancer" at ClinicalTrials.gov
  2. ^ Clinical trial number NCT01348009 for "Tesetaxel Plus Capecitabine and Cisplatin in Advanced Gastric Cancer" at ClinicalTrials.gov
  3. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 21547572, please use {{cite journal}} with |pmid=21547572 instead.


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