Spindle poison
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A spindle poison, also known as a spindle toxin, is a poison that disrupts cell division by affecting the protein threads that connect the centromere regions of chromosomes, known as spindles. Spindle poisons effectively cease the production of new cells by interrupting the mitosis phase of cell division at the spindle assembly checkpoint (SAC). Unfortunately, spindle poisons, as numerous and varied as they are, still are yet to be 100% effective at ending the formation of tumors (neoplasms).
Some spindle poisons:
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