CYP4A11

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Cytochrome P450, family 4, subfamily A, polypeptide 11
Identifiers
Symbols CYP4A11 ; CP4Y; CYP4A2; CYP4AII
External IDs OMIM601310 MGI88611 HomoloGene128044 ChEMBL: 3978 GeneCards: CYP4A11 Gene
EC number 1.14.15.3
RNA expression pattern
PBB GE CYP4A11 217319 x at tn.png
PBB GE CYP4A11 207407 x at tn.png
PBB GE CYP4A11 211231 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1579 13117
Ensembl ENSG00000187048 ENSMUSG00000066072
UniProt Q02928 O88833
RefSeq (mRNA) NM_000778 NM_010011
RefSeq (protein) NP_000769 NP_034141
Location (UCSC) Chr 1:
47.39 – 47.41 Mb
Chr 4:
115.52 – 115.53 Mb
PubMed search [1] [2]

Cytochrome P450 4A11 is a protein that in humans is encoded by the CYP4A11 gene.[1][2]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.[2]

References[edit]

  1. ^ Palmer CN, Richardson TH, Griffin KJ, Hsu MH, Muerhoff AS, Clark JE, Johnson EF (Mar 1993). "Characterization of a cDNA encoding a human kidney, cytochrome P-450 4A fatty acid omega-hydroxylase and the cognate enzyme expressed in Escherichia coli". Biochim Biophys Acta 1172 (1–2): 161–6. doi:10.1016/0167-4781(93)90285-L. PMID 7679927. 
  2. ^ a b "Entrez Gene: CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11". 

Further reading[edit]