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N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase

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N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase
Identifiers
EC no.2.4.1.187
CAS no.118731-82-1
Databases
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BRENDABRENDA entry
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MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase (EC 2.4.1.187, uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase, N-acetylmannosaminyltransferase, UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase, UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase) is an enzyme with systematic name UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol 4-beta-N-acetylmannosaminyltransferase.[1] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol UDP + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyldiphosphoundecaprenol

This enzyme is involved in the biosynthesis of teichoic acid linkage units in bacterial cell walls.

References

  1. ^ Murazumi N, Kumita K, Araki Y, Ito E (December 1988). "Partial purification and properties of UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase from Bacillus subtilis". Journal of Biochemistry. 104 (6): 980–4. PMID 2977387.