April 15 – Babe Ruth hits a solo home run against Howard Ehmke of the Philadelphia Athletics in the first inning. It is Babe's first of the year. The New York Yankees win, 6–3.
May
May 3 :
Jesse and Virgil Barnes became the first brothers in Major League Baseball history to pitch against each other. Virgil prevailed, as the New York Giants defeated Jesse and the Brooklyn Robins, 7–6.
The Pittsburgh Pirates scored a run in the eighth inning and two in the ninth to come from behind and defeat the St. Louis Cardinals 11-10, moving into a tie for first place in the National League.
May 10 – In Detroit, it's Ty Cobb Day and more than 30,000 pay to see the Detroit Tigers legend in his first appearance at Navin Field in a Philadelphia Athletics uniform. With Eddie Collins on base in the first inning, Cobb drives a double into the overflow crowd to send home Collins for the first run of the game, though the Athletics would eventually beat the Tigers 6–3.
May 16 – At Sportsman's Park, 40-year-old Ty Cobb hits a home run in the seventh inning of the Philadelphia Athletics' 10-8 victory over the St. Louis Browns. Cobb, who as a Detroit Tiger had hit one home run in 1905 at age 18 and another in 1906 at age 19, becomes the first player in Major League history to hit a home run before his 20th birthday and after his 40th birthday.
May 22 – The New York Yankees are in high spirits on the road as they beat the host Cleveland Indians at League Park, 7–2, with Babe Ruth hitting his 10th home run of the young season. Ruth's homer is described as a popup that goes over the fence. The Yankees, who wear Indian headdresses during the game, now lead the American League by four and a half games.
Babe Ruth homers for the fourth consecutive game in the fifth inning of the nightcap in Shibe Park. Ruth, who hits his 15th blast against Jack Quinn and his 16th off Howard Ehmke, finishes the month of May with 12 round-trippers. The Yankees lose the opener, 10–3, as the Athletics' Jimmie Foxx hits the first of his 524 major league career home run, which it comes off Yankees pitcher Urban Shocker.
June
June 8 - Tony Lazzeri produces the first regular-season three home run game in New York Yankees history to help savage an 11-inning, 12-11 victory over the Chicago White Sox at Yankee Stadium. Lazzeri drives in five runs from his three homers, the last two with his third, which caps a five-run rally to tie the game in the ninth inning.
July 24 – Babe Ruth hits his 31st home run of the season and his first of 1927 at Comiskey Park. Ruth now has homered in every American League ballpark. The homer, off pitcher Tommy Thomas, breaks a 12-day drought for the Bambino. The Yanks win the game, 3–2.
The New York Yankees are shut out for the only time all season by Lefty Grove and the Philadelphia Athletics.
Tied for first place, the Pittsburgh Pirates sweep a two-game series from the St. Louis Cardinals. They maintain sole possession of first place for the remainder of the season.
September 4 – At Shibe Park in Philadelphia, Babe Ruth hits his 400th career home run and his 44th of the year. The landmark homer comes against Rube Walberg in a 12–2 Yankees win.
September 6 – Babe Ruth and the Yankees come to Fenway Park for a doubleheader. In game 1, Ruth hits his 45th and 46th home runs of the year against Tony Welzer, and the Yankees win, 14–2. One of Ruth's round-trippers clears the center-field fence and is reputedly the longest ever hit at Fenway. In game 2, the Red Sox win, 5–2, despite Ruth's 47th home run, hit against Jack Russell.
September 7 – Babe Ruth follows up on his three-homer day at Fenway Park with two more. Against Danny MacFayden, Ruth hits his 48th and later cracks number 49 against Slim Harriss. The Yankees win, 12–10, and Ruth now has 8 home runs at Fenway Park.
September 11 – Back At Yankee Stadium, Babe Ruth continues his home run barrage. He hits number 50, this one against Milt Gaston of the Browns; the Yankees lose nonetheless, 6–2.
September 13 – A big day for the Yankees and Babe Ruth. In a doubleheader against the Indians, Ruth hits his 51st home run against Willis Hudlin and his 52nd off Joe Shaute. The Yankees win both games by the score of 5–3 and clinch the AL pennant in their 139th game of the season. In addition, Waite Hoyt wins his 20th game.
September 18 – At Yankee Stadium, New York sweeps the Chicago White Sox in a doubleheader, 2–1 and 5–1. In the nightcap, against pitcher Ted Lyons, Babe Ruth hits his 54th home run of the year. Besides, Lou Gehrig weighs in with his third grand slam of 1927.
September 22 – At Yankee Stadium, Babe Ruth homers against Detroit Tigers pitcher Ken Holloway for his 56th of the season. Earl Combs hits three consecutive triples, as the Yankees win, 8-7.
September 27 – Babe Ruth hit a grand slam against Lefty Grove of the Philadelphia Athletics. it is Ruth's 57th home run of the season. The Yankees win, 7-4.
September 29 – Babe Ruth of the New York Yankees hits two homers to tie his own 1921 record of 59 home runs as the Yankees beat the Washington Senators, 15–4.
September 30 – With the score tied 2–2 in the eighth inning, and a runner on third, Babe Ruth hits his 60th home run of the season off Washington Senators pitcher Tom Zachary for a Yankees 4–2 victory. Ruth's 60-HR season-record would not be broken for 34 years.
October
October 2 – Harry Heilmann goes seven-for-nine with a walk in a double header on the final day of the season, as he won his fourth American League batting championship – and led both leagues – with a .398 average. One more hit during the season would have raised his average to .400 for the second time in his career, as Heilmann had hit .403 in 1923.
October 5 – Two errors by the Pittsburgh Pirates lead to three unearned runs as the New York Yankees take game one of the 1927 World Series, 5–4.
October 6 – Once again, sloppy play by the Pittsburgh Pirates helps the Yankees cruise to a game two victory as they score runs on an error, wild pitch and hit batsman.
October 7 – A three-run home run by Babe Ruth caps off a six-run seventh inning as the Yankees cruise to an 8–1 victory in game three of the World Series.
October 8 – The New York Yankees defeat the Pittsburgh Pirates, 4–3, in Game 4 of the World Series, to win their second World Championship, four games to none. This was the first sweep by an American League team over the rival National League. Babe Ruth's fifth-inning home run gives the Yankees a 3–1 lead, but Pittsburgh ties the game later. In the top of the ninth inning, Earle Combswalks, Mark Koenig hits a bunt single, and Ruth walks to fill the bases. Two outs later, a wild pitch rolls far enough away for Combs to score the winning run.
November
November 28 – Billy Evans quits as American League umpire to become business manager of the Cleveland Indians, following the purchase of the club by a group headed by Alva Bradley, to become the first general manager in major league history. Evans, who worked as an AL umpire from 1906 to 1927, became, at age 22, the youngest umpire in major league history, and later became the youngest to officiate in the World Series at age 25.
December
December 2 – The Detroit Tigers send outfielder Heinie Manush along with first baseman Lu Blue to the St. Louis Browns in exchange for shortstop Chick Galloway, outfielder Harry Rice and pitcher Elam Vangilder. Manush, who batted .298 for Detroit in the regular season, will explode in 1928 with the Browns, batting .378 with 104 runs, 90 extra bases, 108 RBI, and a league-leading 241 hits.
January 13 – Bob Ingersoll, 44, pitcher for the 1914 Cincinnati Reds.
January 27 – Drummond Brown, 41, pitcher from 1912 to 1914 for the National League Boston Braves and the Kansas City Packers of the Federal League.
February
February 11 – Bobby Rothermel, 56, infielder who played with the 1899 Baltimore Orioles.
February 13 – Vive Lindaman, 49, pitcher for the Boston Doves/Beaneaters of the National League from 1906 to 1909.
February 17 – Harry Little, 76, outfielder/second baseman for the St. Louis Brown Stockings and Louisville Grays of the National League during the 1877 season.
February 19 – Katsy Keifer, 35, pitcher for the 1914 Indianapolis Hoosiers of the Federal League.
February 21 – Ike Rockenfield, 50, second baseman for the St. Louis Browns of the American League in the 1905 and 1906 seasons.
February 24 – Charlie Bennett, 72, star catcher whose career was ended when a train accident cost him his legs.
March
March 4 – Horace Wilson, 84, American professor of English at Tokyo University during the modernization of Japan after the Meiji Restoration, who is credited with introducing baseball to Japan in either 1872 or 1873.
March 6 – John Tilley, 72, left fielder for the Cleveland Blues, Toledo BlueStockings and St. Paul WhiteCaps in parts of two seasons spanning 1882–1884.
March 16 – Jake Wells, 63, catcher and left fielder for the 1888 Detroit Wolverines and the 1890 St. Louis Browns.
March 27 – Joe Start, 84, prominent first baseman of the 1860s and 1870s.
April
April 1 – Ben Harris, 37, pitcher for the Kansas City Packers of the Federal League from 1914 to 1915.
April 2 – Mike Lynch, 46, pitcher for the Pittsburgh PIrates and New York Giants from 1904 through 1907.
April 7 – Billy Alvord, 63, third baseman for five seasons from 1885 to 1893.
April 7 – Ray Miller, 39, pitcher for the Cleveland Indians and the Pittsburgh Pirates in 1917.
April 13 – Kirtley Baker, 57, National League pitcher for the Pittsburgh Alleghenys, Baltimore Orioles and Washington Senators in parts of five seasons spanning 1890–1899.
April 13 – Tommy Johns, 75, left fielder for the Baltimore Marylands of the National Association during the 1873 season.
April 18 – Pop Smith, 70, infielder for 12 seasons from 1880 to 1891.
April 26 – Bill Gannon, 54, outfielder for the Chicago Orphans of the National League in 1901.
May
May 3 – Otto Schomberg, 62, first baseman and right fielder for the 1886 Pittsburgh Alleghenys of the American Association and the 1887-88 Indianapolis Hoosiers of the National League.
May 16 – Pat Murphy, 70, backup catcher who played from 1887 through 1890 for the New York Giants of the National League.
May 18 – Patrick O'Loughlin, 67, Irish outfielder who appeared in one game for the 1883 Baltimore Orioles of the American Association.
May 26 – Herm Merritt, 26, shortstop for the 1921 Detroit Tigers of the American League.
June
June 7 – Pat Griffin, 34, pitcher for the 1914 Cincinnati Reds of the National League.
June 18 – Jack Harper, 33, pitcher for the 1915 Philadelphia Athletics of the American League.
August
August 6 – Chick Pedroes, 57, Cuban outfielder in two games for the 1902 Chicago Cubs of the National League.
August 8 – Billy Gilbert, 51, second baseman for four different teams from 1901 through 1909, and member of the 1905 New York Giants World Champion team.
August 16 – Jerry Denny, 68, third baseman for seven National League teams in 13 seasons spanning 1881-94.
August 22 – Mike Shea, 60, pitcher in two games for the 1887 Cincinnati Red Stockings of the American Association.
August 25 – Harry Cheek, 48, backup catcher for the 1910 Philadelphia Phillies of the National League.
September
September 6 – Lave Cross, 61, third baseman and catcher for over 20 seasons, captain of the 1902 and 1905 AL champion Philadelphia Athletics, and one of the first ten players to collect 2,500 hits.
September 27 – Ben Hunt, 38, pitched for the Red Sox and Cardinals in the early 1910s.
September 30 – Hank Morrison, 61, pitcher for the 1887 Indianapolis Hoosiers of the National League.
October
October 4 – John Richter, 54, third baseman for the 1898 Louisville Colonels of the National League.
October 11 – Mike Corcoran, 69, pitcher in one game for the 1884 Chicago White Stockings of the National League.
October 14 – Ed Hughes, 47, pitcher for the Boston Americans of the American League in the 1905 and 1906 seasons.
October 22 – Ross Youngs, 30, Hall of Fame right fielder who hit a career .322 batting average for the New York Giants over 10 seasons from 1917 to 1926, which included four National League pennants and two World Series championships in 1921 and 1922.
October 25 – Tom Brown, 67, outfielder who played from 1892 through 1898 for nine teams in four different leagues, collecting 1951 hits in 1788 games, while managing two seasons for the 1897–1898 Washington Senators, and umpiring three full seasons.
November
November 7 – Ed Clark, 64, pitcher for the 1886 Philadelphia Athletics of the American Association,
November 8 – Phil Bedgood, 29, pitcher from 1922 to 1923 for the Cleveland Indians of the American League.
November 22 – John McGlone, 66, third baseman for the 1886 Washington Senators of the National League and the 1887-88 Cleveland Blues of the American Association.
November 30 – Jimmy Wood, 84, player/manager for the Chicago White Stockings, Troy Haymakers, Brooklyn Eckfords and Philadelphia White Stockings from 1871 to 1873, who hit .333 in 102 games and posted a 105–99 managerial record.
December
December 1 – Danny Shay, 51, shortstop for the Cleveland Blues, St. Louis Cardinals and New York Giants in parts of four seasons spanning 1901-07.
December 1 – Germany Smith, 64, shortstop who played from 1884 through 1898 for seven different teams, most notably for the Brooklyn Grays/Bridegrooms during seven seasons.
December 17 – Bill Gilbert, 59, pitcher for the 1892 Baltimore Orioles of the National League.
December 24 – Al Myers, 64, second baseman who played from 1894 to 1891 for five teams, most prominently with the Washington Nationals of the National League.
December 31 – Jack Sharrott, 58, pitcher/outfielder who posted a 20–17 record with a 3.12 ERA and a .237 batting average for the New York Giants and Philadelphia Phillies from 1890 to 1893.
