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Selenide, water dikinase

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selenide, water dikinase
Identifiers
EC no.2.7.9.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a selenide, water dikinase (EC 2.7.9.3) is an enzyme that catalyzes the chemical reaction

ATP + selenide + H2O AMP + selenophosphate + phosphate

The 3 substrates of this enzyme are ATP, selenide, and H2O, whereas its 3 products are AMP, selenophosphate, and phosphate.

This enzyme belongs to the family of transferases, to be specific, those transferring phosphorus-containing groups (phosphotransferases) with paired acceptors (dikinases). The systematic name of this enzyme class is ATP:selenide, water phosphotransferase. This enzyme is also called selenophosphate synthetase. This enzyme participates in selenoamino acid metabolism.

References

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  • Veres Z, Tsai L, Scholz TD, Politino M, Balaban RS, Stadtman TC (1992). "Synthesis of 5-methylaminomethyl-2-selenouridine in tRNAs: 31P NMR studies show the labile selenium donor synthesized by the selD gene product contains selenium bonded to phosphorus". Proc. Natl. Acad. Sci. U.S.A. 89 (7): 2975–9. Bibcode:1992PNAS...89.2975V. doi:10.1073/pnas.89.7.2975. PMC 48786. PMID 1557403.