Atrolysin F
| Atrolysin F | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.24.45 | ||||||||
| CAS no. | 172306-52-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Atrolysin F (EC 3.4.24.45, Crotalus atrox metalloendopeptidase, hemorrhagic toxin f, Crotalus atrox metalloendopeptidase f) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- Cleavage of Val2-Asn, Gln4-His, Leu6-Cys, His10-Leu, Ala14-Leu and Tyr16-Leu bonds in insulin B chain
This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).
References
- ^ Nikai, T.; Mori, N.; Kishida, M.; Sugihara, H.; Tu, A.T. (1984). "Isolation and biochemical characterization of hemorrhagic toxin f from the venom of Crotalus atrox (western diamondback rattlesnake)". Arch. Biochem. Biophys. 231: 309–319. doi:10.1016/0003-9861(84)90393-x. PMID 6375570.
External links
- Atrolysin+F at the U.S. National Library of Medicine Medical Subject Headings (MeSH)