Aviv Regev
Aviv Regev | |
---|---|
![]() Regev at the Intelligent Systems for Molecular Biology conference in 2017 | |
Born | [3] | July 11, 1971
Alma mater | Tel Aviv University (M.Sc., Ph.D.) |
Awards |
|
Scientific career | |
Fields | Bioinformatics Computational Biology |
Institutions | |
Doctoral advisor | Eva Jablonka Ehud Shapiro |
Website | www |
Aviv Regev (born 11 July 1971)[3] is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche.[4] She is a core member (on leave) at the Broad Institute of MIT and Harvard and professor (on leave) at the Department of Biology of the Massachusetts Institute of Technology.[5] Regev is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits. She founded and leads the Human Cell Atlas project,[6] together with Sarah Teichmann.
Education
[edit]Regev studied at the Adi Lautman Interdisciplinary Program for Outstanding Students of Tel Aviv University, where she completed her PhD under the supervision of Eva Jablonka,[7] and Ehud Shapiro.[8]
Career and research
[edit]In 2020, Regev became the Head and Executive Vice President of Genentech Research and Early Development, based in South San Francisco, and a member of the extended Corporate Executive Committee of Roche.[9][10] Previously, she was a Core Institute Member (now on leave), Chair of the Faculty, Founding Director of the Klarman Cell Observatory and co-Director Cell Circuits Program at the Broad Institute of MIT and Harvard. She was also a professor in the Department of Biology at the Massachusetts Institute of Technology (now on leave), as well as an Investigator at the Howard Hughes Medical Institute. Regev's research[11] includes work on gene expression[12][13] (with Eran Segal and David Botstein), and the use of π-calculus to represent biochemical processes.[14][15][16] Regev's team has been a leading pioneer of single-cell genomics experimental and computational methods.[17] In 2014, she pitched the idea of the creation of Human Cell Atlas,[18] a project to describe all cell types in the human body. Regev founded the Human Cell Atlas together with Sarah Teichmann along with collaborators all over the world.[citation needed]
Single Cell Genomics
[edit]Regev's lab pioneered the development and application of many of the key experimental and computational advances for single cell and spatial genomics, especially single cell RNA-Seq (scRNA-seq).
Awards and honors
[edit]Regev is a fellow of the International Society of Computational Biology (ISCB) (2017),[19] a Helmholtz Fellow (2020),[20] and a fellow of the American Association for Cancer Research (AACR) (2021).[21] She is a member of the US National Academy of Sciences (NAS, elected 2019)[22] and of the US National Academy of Medicine (NAM, elected 2020).[23] She was elected as a foreign member of the Royal Society [24] and as an associate member of the European Molecular Biology Organization in 2024.[25]
- TED AI 2023 Talk: Can AI Help Develop New Medicines[26]
- 25th L'Oréal-UNESCO For Women in Science Awards (Laureate for North America), 2023[27]
- Elected to the American Academy of Arts and Sciences, 2022[28]
- Anderson Lecture, University of Virginia, 2022[29]
- Nakasone Award from the Human Frontiers Science Program (2022)[30]
- Honorary doctorate, ETH Zurich (2021)[31]
- Ernst Schering Prize (2021)[32]
- James Prize in Science and Technology Integration, National Academy of Sciences (2021)[33]
- Vanderbilt Prize (2021)[34]
- She was awarded the 25th Keio Medical Science Prize in 2020.[35][36]
- AACR-Irving Weinstein Foundation Distinguished Lecture (2021)[37]
- Lurie Prize from the Foundation for the NIH (FNIH) (2020)[38]
- Mendel Lecture, European Society of Human Genetics (2020)[39]
- Jonathan Kraft Prize from Massachusetts General Hospital (2020)[40]
- FASEB Excellence in Science Mid-Career Investigator Award (2019)[41]
- She was elected a member of the National Academy of Sciences (NAS) in 2019.[42]
- She also served on the Life Sciences jury for the Infosys Prize in 2018.
- Weatherall Lecture, University Oxford, UK (2018)[43]
- Harvey Lecture, Harvey Society, New York (2018)[44]
- McCormick Lecture, Stanford University (2018)[45]
- Paul Marks Prize for Cancer Research (2017).[46]
- ISCB Innovator Award in 2017.[2][47]
- Earl and Thressa Stadtman Scholar Award from the American Society of Biochemistry and Molecular Biology (ASBMB) (2014)[48]
- Burroughs Wellcome Fund Career Award.[49]
- In 2008, she was also awarded the NIH Director's Pioneer Award.[50][51]
- Regev was awarded the Overton Prize in 2008 for "outstanding accomplishment to a scientist in the early to mid stage of his or her career".[1]
References
[edit]- ^ a b Sansom, C.; Morrison Mckay, B. J. (2008). Bourne, Philip E. (ed.). "ISCB Honors David Haussler and Aviv Regev". PLOS Computational Biology. 4 (7): e1000101. Bibcode:2008PLSCB...4E0101S. doi:10.1371/journal.pcbi.1000101. PMC 2536508. PMID 18795145.
- ^ a b Fogg, Christiana N.; Kovats, Diane E.; Berger, Bonnie (2017). "2017 ISCB Innovator Award: Aviv Regev". PLOS Computational Biology. 13 (6): e1005558. Bibcode:2017PLSCB..13E5558F. doi:10.1371/journal.pcbi.1005558. ISSN 1553-7358. PMC 5493285. PMID 28665936.
- ^ a b "Aviv Regev" (PDF). broadinstitute.org. Archived from the original (PDF) on 16 November 2017. Retrieved 2 December 2021.
- ^ GENENTECH EXECUTIVE COMMITTEE, accessed 6 August 2020.
- ^ "Aviv Regev at MIT". biology.mit.edu. Archived from the original on 6 April 2017. Retrieved 5 November 2017.
- ^ Nowogrodzki, Anna (5 July 2017). "How to build a human cell atlas". Nature. 547 (7661): 24–26. Bibcode:2017Natur.547...24N. doi:10.1038/547024a. PMID 28682347. S2CID 211067156.
- ^ Regev, A.; Lamb, M. J.; Jablonka, E. (1998). "The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?". Molecular Biology and Evolution. 15 (7): 880. doi:10.1093/oxfordjournals.molbev.a025992. ISSN 0737-4038.
- ^ Regev, A.; Shapiro, E. (2002). "Cellular abstractions: Cells as computation". Nature. 419 (6905): 343. Bibcode:2002Natur.419..343R. doi:10.1038/419343a. PMC 3842595. PMID 12353013.
- ^ Taylor, Nick Paul (11 May 2020). "Genentech lures Regev from Broad Institute to lead research and early development". fiercebiotech.com. Retrieved 25 May 2020.
- ^ "Changes to the Roche Enlarged Corporate Executive Committee" (Press release). Basel, Switzerland: F. Hoffmann-La Roche Ltd. globenewswire. 11 May 2020. Retrieved 25 May 2020.
- ^ Search Results for author Regev A on PubMed.
- ^ Segal, E.; Shapira, M.; Regev, A.; Pe'er, D.; Botstein, D.; Koller, D.; Friedman, N. (2003). "Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data". Nature Genetics. 34 (2): 166–176. doi:10.1038/ng1165. PMID 12740579. S2CID 6146032.
- ^ Segal, E.; Friedman, N.; Koller, D.; Regev, A. (2004). "A module map showing conditional activity of expression modules in cancer". Nature Genetics. 36 (10): 1090–1098. doi:10.1038/ng1434. PMC 2271138. PMID 15448693.
- ^ Regev, A.; Silverman, W.; Shapiro, E. (2001). "Representation and simulation of biochemical processes using the pi-calculus process algebra". Pacific Symposium on Biocomputing: 459–470. doi:10.1142/9789814447362_0045. ISBN 978-981-02-4515-3. PMID 11262964.
- ^ Priami, C.; et al. (2001). "Application of a stochastic name-passing calculus to representation and simulation of molecular processes" (PDF). Information Processing Letters. 80: 25–31. doi:10.1016/S0020-0190(01)00214-9.
- ^ Study provides insight into regenerative potential of prostate gland, News Medical, accessed 4 May 2020.
- ^ "Aviv Regev". HHMI.org. Retrieved 11 May 2020.
- ^ The Human Cell Atlas – Aviv Regev, retrieved 30 May 2022
- ^ "2017 ISCB Innovator Award: Aviv Regev". www.iscb.org. Retrieved 14 March 2022.
- ^ "Event – Helmholtz Zentrum München". www.helmholtz-munich.de. Retrieved 14 March 2022.
- ^ "Aviv Regev, PhD, FAACR | Scientific Awards | AACR". American Association for Cancer Research (AACR). Retrieved 14 March 2022.
- ^ "Aviv Regev". www.nasonline.org. Retrieved 14 March 2022.
- ^ "National Academy of Medicine Elects 100 New Members". National Academy of Medicine. 19 October 2020. Retrieved 14 March 2022.
- ^ "Outstanding scientists elected as Fellows of the Royal Society".
- ^ "EMBO elects 2024 members".
- ^ "Aviv Regev: Can AI Help Develop New Medicines".
- ^ "Discover the laureates of the 25th L'Oréal-UNESCO For Women in Science International Awards | UNESCO". www.unesco.org. Retrieved 2 June 2023.
- ^ "New Members". American Academy of Arts & Sciences. Retrieved 30 May 2022.
- ^ "The Events Calendar".
- ^ "Press Release – 2022 HFSP Nakasone Award".
- ^ Foppa, Carolin Arndt (22 November 2021). "Pioneer in bioinformatics receives ETH Honorary doctorate". bsse.ethz.ch. Retrieved 18 March 2022.
- ^ "Ernst Schering Prize 2021 – Schering Stiftung". Retrieved 18 March 2022.
- ^ "James Prize in Science and Technology Integration". www.nasonline.org. Retrieved 18 March 2022.
- ^ Snyder, Bill. "Regev receives Vanderbilt Prize in Biomedical Science". Vanderbilt University. Retrieved 18 March 2022.
- ^ "Award Ceremony for the 25th Keio Medical Science Prize". keio.ac.jp. Retrieved 22 December 2020.
- ^ "Announcement of the 25th Keio Medical Science Prize – News – Keio University Medical Science Fund". www.ms-fund.keio.ac.jp. Retrieved 18 March 2022.
- ^ "Aviv Regev, PhD, FAACR | Scientific Awards | AACR". American Association for Cancer Research (AACR). Retrieved 18 March 2022.
- ^ "2020 FNIH Lurie Prize in Biomedical Sciences Winner Pioneered Innovative Techniques to Shed New Light on Human Health | The Foundation for the National Institutes of Health". fnih.org. 18 June 2020. Retrieved 18 March 2022.
- ^ Wimmer, Doris. "Aviv Regev". ESHG Conference 2020. Retrieved 14 March 2022.
- ^ "Kraft Prize Symposium". Massachusetts General Hospital. Retrieved 14 March 2022.
- ^ "Past Recipients". www.faseb.org. Retrieved 14 March 2022.
- ^ "2019 NAS Election". nasonline.org. Retrieved 30 April 2019.
- ^ "Weatherall Lectures — MRC Weatherall Institute of Molecular Medicine". www.imm.ox.ac.uk. Retrieved 14 March 2022.
- ^ "The Harvey Society: Series 113, Lecture 5". harveysociety.org. Retrieved 14 March 2022.
- ^ "MIT's Aviv Regev to present annual McCormick Lecture Feb. 1". News Center (in Samoan). Retrieved 14 March 2022.
- ^ "2017 Prize Winners". Memorial Sloan Kettering Cancer Center. Retrieved 12 December 2017.
- ^ "February 09, 2017: ISCB Announces 2017 Award Recipients". iscb.org. Retrieved 10 February 2017.
- ^ "Regev recognized for rigorous integration of experimental and computational approaches". www.asbmb.org. Retrieved 14 March 2022.
- ^ Dynamic single-cell imaging of direct reprogramming reveals an early specifying event – Nature Biotechnology: Aviv Regev, Ph.D. – Career Awards at the Scientific Interface; Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs – Nature Biotechnology: Aviv Regev, Ph.D. – Career Awards at the Scientific Interface.
- ^ "Three faculty win '08 NIH Pioneer Awards". MIT News | Massachusetts Institute of Technology. 22 September 2008. Retrieved 6 March 2022.
- ^ "2008 NIH Director's Pioneer Award". Archived from the original on 30 July 2019. Retrieved 30 July 2019.
- Living people
- Computational biologists
- Systems biologists
- Israeli bioinformaticians
- Massachusetts Institute of Technology School of Science faculty
- Overton Prize winners
- Howard Hughes Medical Investigators
- Tel Aviv University alumni
- Fellows of the International Society for Computational Biology
- Adi Lautman Interdisciplinary Program for Outstanding Students alumni
- Members of the United States National Academy of Sciences
- Genentech people
- Women computational biologists
- 1970 births
- 21st-century Israeli women scientists
- 21st-century biologists
- Israeli women computer scientists
- Members of the National Academy of Medicine