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Systematic (IUPAC) name
Clinical data
Legal status
Routes of
Pharmacokinetic data
Biological half-life 106 hours
CAS Number 2647-50-9 YesY
PubChem CID 12947024
ChemSpider 10441497
Chemical data
Formula C15H10BrFN2O
Molar mass 333.16 g/mol

Flubromazepam is a benzodiazepine derivative which was first synthesized in 1960,[1] but was never marketed and did not receive any further attention or study until late 2012 when it appeared on the grey market as a novel designer drug.[2][3][4][5]

It is a structural analog of phenazepam in which the chlorine atom has been replaced by a fluorine atom.

An alternate isomer, 5-(2-bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one, may have been sold under the same name.[2]

Alternate isomer

See also[edit]


  1. ^ US 3136815, "Amino substituted benzophenone oximes and derivatives thereof" 
  2. ^ a b Bjoern Moosmann, Laura M. Huppertz, Melanie Hutter, Armin Buchwald, Sascha Ferlaino, Volker Auwärter (November 2013). "Detection and identification of the designer benzodiazepine flubromazepam and preliminary data on its metabolism and pharmacokinetics". Journal of Mass Spectrometry 48 (11): 1150–1159. doi:10.1002/jms.3279. PMID 24259203. 
  3. ^ B. Moosmann, M. Hutter, L. M. Huppertz, V. Auwärter. "Characterization of the designer benzodiazepines pyrazolam and flubromazepam and study on their detectability in human serum and urine samples" (PDF). Institute of Forensic Medicine, Forensic Toxicology, University Medical Center Freiburg, Freiburg, Germany. 
  4. ^ Lauren C. O'Connor, Hazel J. Torrance, Denise A. McKeown (October 2015). "ELISA Detection of Phenazepam, Etizolam, Pyrazolam, Flubromazepam, Diclazepam and Delorazepam in Blood Using Immunalysis® Benzodiazepine Kit". Journal of Analytical Toxicology. doi:10.1093/jat/bkv122. PMID 26518230. 
  5. ^ "Flubromazepam". New Synthetic Drugs Database.