Girisopam

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Girisopam
Girisopam.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C18H17ClN2O2
Molar mass 328.79
3D model (JSmol)
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Girisopam[1] (GYKI-51189, EGIS-5810) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam[2] and zometapine. It has selective anxiolytic action with no sedative, anticonvulsant or muscle relaxant effects.[3][4][5]

See also[edit]

References[edit]

  1. ^ US Patent 4322346
  2. ^ Psychotropics.dk
  3. ^ Andrási F, Horváth K, Sineger E, Berzsenyi P, Borsy J, Kenessey A, Tarr M, Láng T, Kórösi J, Hámori T. Neuropharmacology of a new psychotropic 2,3-benzodiazepine. Arzneimittelforschung. 1987 Oct;37(10):1119-24.
  4. ^ Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
  5. ^ Horváth EJ, Salamon C, Bakonyi A, Fekete MI, Palkovits M. [(3)H]-girisopam, a novel selective benzodiazepine for the 2, 3-benzodiazepine binding site. Brain Research. Brain Research Protocols. 1999 Jul;4(2):230-5.