Hepatic fructokinase

ketohexokinase (fructokinase)
ketohexokinase (fructokinase)
Identifiers
Symbol	KHK
NCBI gene	3795
HGNC	6315
OMIM	229800
RefSeq	NM_006488
UniProt	P50053
Other data
EC number	2.7.1.3
Locus	Chr. 2 p23.3-23.2
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Hepatic fructokinase (or ketohexokinase ) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.

ATP +

\longrightarrow

ADP +

ATP + D-fructose → ADP + D-fructose-1-phosphate^[1]

Pathology

A deficiency is associated with essential fructosuria.

Hepatic+fructokinase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This EC 2.7 enzyme-related article is a stub. You can help Wikipedia by expanding it.

v t e Metabolism: carbohydrate metabolism fructose and galactose enzymes
Fructose / Fructolysis	Hepatic fructokinase Aldolase B Triokinase
Sorbitol	Sorbitol dehydrogenase Aldose reductase
Galactose / Galactolysis	Galactokinase Galactose-1-phosphate uridylyltransferase/UDP-glucose 4-epimerase Aldose reductase Galactose mutarotase^[1]
Lactose	Lactose synthase Lactase
Mannose	Mannose phosphate isomerase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)