MMP25

MMP25
Identifiers
Aliases	MMP25, MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6, matrix metallopeptidase 25
External IDs	OMIM: 608482; MGI: 2443938; HomoloGene: 23375; GeneCards: MMP25; OMA:MMP25 - orthologs
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	23,864,251 bp
RNA expression pattern
	Top expressed in
	blood; ; spleen; ; vena cava; ; olfactory bulb; ; sperm; ; periodontal fiber; ; appendix; ; body of tongue; ; cervix epithelium; ; bone marrow;
	Top expressed in
	granulocyte; ; epiblast; ; bone marrow; ; trigeminal ganglion; ; embryo; ; embryo; ; morula; ; tail of embryo; ; thymus; ; neural tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; peptidase activity; metalloendopeptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding;
Cellular component	integral component of membrane; extracellular region; anchored component of membrane; membrane; plasma membrane; specific granule membrane; extracellular matrix; extracellular space;
Biological process	inflammatory response; hard palate development; proteolysis; neutrophil degranulation; extracellular matrix organization; collagen catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	64386
	240047
	n/a
	ENSMUSG00000023903
	Q9NPA2
	Q3U435
	NM_004142; NM_022468; NM_022718
	NM_001033339; NM_001320258
	NP_071913
	NP_001028511; NP_001307187
	Wikidata
View/Edit Human	View/Edit Mouse

Matrix metalloproteinase-25 is an enzyme that in humans is encoded by the MMP25 gene.^[4]^[5]^[6]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023903 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Pei D (Feb 2000). "Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage". Cell Res. 9 (4): 291–303. doi:10.1038/sj.cr.7290028. PMID 10628838.
^ Velasco G, Cal S, Merlos-Suarez A, Ferrando AA, Alvarez S, Nakano A, Arribas J, Lopez-Otin C (Mar 2000). "Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors". Cancer Res. 60 (4): 877–82. PMID 10706098.
^ "Entrez Gene: MMP25 matrix metallopeptidase 25".

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

v t e Proteases: metalloendopeptidases (EC 3.4.24)
ADAM proteins	Alpha secretases ADAM9 ADAM10 ADAM17 ADAM19 ADAM2 ADAM7 ADAM8 ADAM11 ADAM12 ADAM15 ADAM18 ADAM22 ADAM23 ADAM28 ADAM33 ADAMTS1 ADAMTS2 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS8 ADAMTS9 ADAMTS10 ADAMTS12 ADAMTS13
Matrix metalloproteinases	Collagenases MMP1 MMP8 Gelatinases MMP2 MMP9 MMP3 MMP7 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP16 MMP17 MMP19 MMP20 MMP21 MMP23A MMP23B MMP24 MMP25 MMP26 MMP27 MMP28
Other	Neprilysin Procollagen peptidase Thermolysin Pregnancy-associated plasma protein A Bone morphogenetic protein 1 Lysostaphin Insulin-degrading enzyme ZMPSTE24