Mitochondrial myopathy

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Mitochondrial myopathy
Animal mitochondrion diagram en (edit).svg
Simplified structure of a typical mitochondrion
Classification and external resources
Specialty neurology
ICD-10 G71.3
MeSH D017240

Mitochondrial myopathies are types of myopathies associated with mitochondrial disease. [1]On biopsy, the muscle tissue of patients with these diseases usually demonstrate "ragged red" muscle fibers. These ragged-red fibers contain mild accumulations of glycogen and neutral lipids, and may show an increased reactivity for succinate dehydrogenase and a decreased reactivity for cytochrome c oxidase. Inheritance is maternal (non-Mendelian extranuclear). There are several subcategories of mitochondrial myopathies.

Signs and symptoms[edit]

Signs and symptoms include (for each of the following causes):

Diagnosis[edit]

Treatment[edit]

Although no cure currently exists, there is hope in treatment for this class of hereditary diseases with the use of an embryonic mitochondrial transplant.[2]

References[edit]

  1. ^ "Mitochondrial Myopathy Information Page | National Institute of Neurological Disorders and Stroke". www.ninds.nih.gov. Retrieved 2017-02-28. 
  2. ^ "Three-parent embryo formed in lab" (web). Scientists believe they have made a potential breakthrough in the treatment of serious disease by creating a human embryo with three separate parents. BBC News. 5 February 2008. Retrieved 2008-02-08. 

External links[edit]