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Virus classification
Group IV ((+)ssRNA)
Type Species
  • Newbury-1 virus

Nebovirus is a genus of viruses, in the family Caliciviridae[1]. Bovine serve as natural hosts. There is currently only one species in this genus: the type species Newbury-1 virus.[2] Diseases associated with this genus include: necrotizing hepatitis leading to fatal hemorrhages.[3]


Group: ssRNA(+)



Viruses in Nebovirus are non-enveloped, with icosahedral geometries, and T=3, T=1 symmetry. The diameter is around 35 nm. Genomes are linear and non-segmented, around 8.3kb in length.[3]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Nebovirus Icosahedral T=1, T=3 Non-enveloped Linear Monopartite

Life cycle[edit]

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by RNA termination-reinitiation. Bovine serve as the natural host.[3]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Nebovirus Bovine Liver Cell receptor endocytosis Lysis Cytoplasm Cytoplasm Unknown


  1. ^ Vinjé, J; Estes, MK; Esteves, P; Green, KY; Katayama, K; Knowles, NJ; L'Homme, Y; Martella, V; Vennema, H; White, PA; ICTV Report Consortium (November 2019). "ICTV Virus Taxonomy Profile: Caliciviridae". The Journal of General Virology. 100 (11): 1469–1470. doi:10.1099/jgv.0.001332. PMID 31573467.
  2. ^ a b "ICTV Report Caliciviridae".
  3. ^ a b c "Viral Zone". ExPASy. Retrieved 13 August 2015.

External links[edit]