Phosphoglucokinase

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phosphoglucokinase
Identifiers
EC number2.7.1.10
CAS number9032-96-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a phosphoglucokinase (EC 2.7.1.10) is an enzyme that catalyzes the chemical reaction

ATP + alpha-D-glucose 1-phosphate ADP + alpha-D-glucose 1,6-bisphosphate

Thus, the two substrates of this enzyme are ATP and alpha-D-glucose 1-phosphate, whereas its two products are ADP and alpha-D-glucose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase. Other names in common use include glucose-phosphate kinase, phosphoglucokinase (phosphorylating), and ATP:D-glucose-1-phosphate 6-phosphotransferase. This enzyme participates in starch and sucrose metabolism.

References[edit]

  • Paladini AC, Caputto R (August 1949). "The enzymatic synthesis of glucose-1,6-diphosphate". Archives of Biochemistry. 23 (1): 55–66. PMID 18135764.