ST8SIA4

ST8SIA4
Identifiers
Aliases	ST8SIA4, PST, PST1, SIAT8D, ST8SIA-IV, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
External IDs	OMIM: 602547 MGI: 106018 HomoloGene: 4147 GeneCards: ST8SIA4
Gene location (Human)
Chr.	Chromosome 5 (human)
End	100,903,282 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	95,667,571 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; blood; ; monocyte; ; trabecular bone; ; visceral pleura; ; bone marrow; ; lymph node; ; amniotic fluid; ; bone marrow cells; ; placenta;
	Top expressed in
	fossa; ; median eminence; ; medial ganglionic eminence; ; blood; ; motor neuron; ; substantia nigra; ; suprachiasmatic nucleus; ; superior cervical ganglion; ; supraoptic nucleus; ; arcuate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sialyltransferase activity; sialic acid binding; glycosyltransferase activity; transferase activity; alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;
Cellular component	integral component of membrane; Golgi membrane; membrane; Golgi apparatus;
Biological process	nervous system development; protein glycosylation; N-glycan processing; ganglioside biosynthetic process; oligosaccharide metabolic process; sialylation;
	Sources:Amigo / QuickGO
Orthologs
	7903
	20452
	ENSG00000113532
	ENSMUSG00000040710
	Q92187
	Q64692
	NM_005668; NM_175052
	NM_001159745; NM_009183
	NP_005659; NP_778222
	NP_001153217; NP_033209
	Wikidata
View/Edit Human	View/Edit Mouse

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase is an enzyme that in humans is encoded by the ST8SIA4 gene.^[5]^[6]

References

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)