Streptolysin
Streptolysin is a streptococcal hemolytic exotoxin.[1][2]
Types include Streptolysin O (SLO), which is oxygen-labile, and Streptolysin S (SLS), which is oxygen-stable.[3]
An antibody, anti-streptolysin O, can be detected in an antistreptolysin O titre.
Streptolysin O is hemolytically active only in a reversibly reduced state unlike Streptolysin S which is stable in the presence of oxygen. Another difference is that that SLO is antigenic while SLS is non antigenic due to its small size.
References
- ^ "streptolysin" at Dorland's Medical Dictionary
- ^ Streptolysin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ^ Sierig G, Cywes C, Wessels MR, Ashbaugh CD (2003). "Cytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococci". Infect. Immun. 71 (1): 446–55. doi:10.1128/IAI.71.1.446-455.2003. PMC 143243. PMID 12496195.
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