Tupavirus
| Tupavirus | |
|---|---|
| Virus classification | |
| Group: | Group V ((−)ssRNA)
|
| Order: | |
| Family: | |
| Genus: | Tupavirus
|
| Type species | |
| Durham tupavirus | |
| Species | |
| |
Tupavirus is a genus of viruses in the family Rhabdoviridae, order Mononegavirales.[1][2]
Taxonomy
| Genus | Species | Virus (Abbreviation) |
| Tupavirus | Durham tupavirus* | Durham virus (DURV) |
| Tupaia tupavirus | tupaia virus (TUPV) |
Table legend: "*" denotes type species.
Structure
Tupavirions enveloped, with bullet shaped geometries. These particles are about 160 nm long. Tupavirus genomes are linear, around 11.2 kb in length. The genome codes for 7 proteins.[1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Tupavirus | Bullet-shaped | Enveloped | Linear |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral G glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding, and tubule-guided viral movement. Birds serve as the natural host.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Tupavirus | Birds | None | Clathrin-mediated endocytosis | Budding | Cytoplasm | Cytoplasm | Unknown |
References
- ^ a b c "Viral Zone". ExPASy. Retrieved 13 August 2015.
- ^ ICTV. "Virus Taxonomy: 2014 Release". Retrieved 13 August 2015.
- ^ Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier (1 August 2016). "Taxonomy of the order Mononegavirales: update 2016". Archives of Virology. 161 (8): 2351–2360. doi:10.1007/s00705-016-2880-1. ISSN 1432-8798. PMC 4947412. PMID 27216929.