Undecaprenyl-diphosphooligosaccharide-protein glycotransferase
| Undecaprenyl-diphosphooligosaccharide-protein glycotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.99.19 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Undecaprenyl-diphosphooligosaccharide-protein glycotransferase (EC 2.4.99.19, PglB) is an enzyme with systematic name tritrans,heptacis-undecaprenyl-diphosphooligosaccharide:protein-L-asparagine N-beta-D-oligosaccharidotransferase.[1][2] This enzyme catalyses the following chemical reaction
- tritrans,heptacis-undecaprenyl diphosphooligosaccharide + [protein]-L-asparagine tritrans,heptacis-undecaprenyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to protein L-asparagine
This is a bacterial enzyme that is isolated from Campylobacter jejuni and Campylobacter lari.
References
- ^ Maita, N.; Nyirenda, J.; Igura, M.; Kamishikiryo, J.; Kohda, D. (2010). "Comparative structural biology of eubacterial and archaeal oligosaccharyltransferases". J. Biol. Chem. 285 (7): 4941–4950. doi:10.1074/jbc.M109.081752. PMID 20007322.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Lizak, C.; Gerber, S.; Numao, S.; Aebi, M.; Locher, K.P. (2011). "X-ray structure of a bacterial oligosaccharyltransferase". Nature. 474: 350–355. doi:10.1038/nature10151. PMID 21677752.
External links
- Undecaprenyl-diphosphooligosaccharide-protein+glycotransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)