Xipapillomavirus

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Xipapillomavirus
Virus classification
Group:
Group I (dsDNA)
Family:
Genus:
Xipapillomavirus
Type Species

Xipapillomavirus is a genus of viruses, in the family Papillomaviridae[1]. Bovine serve as natural hosts. There are currently five species in this genus including the type species Xipapillomavirus 1. Diseases associated with this genus include: true papillomas on the cutaneous or mucosal surfaces of cattle.[2][3]

Taxonomy[edit]

Group: dsDNA

[3]

Structure[edit]

Viruses in Xipapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 7kb in length. The genome has 6 open reading frames.[2]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Xipapillomavirus Icosahedral T=7 Non-enveloped Circular Monopartite

Life cycle[edit]

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Bovine serve as the natural host. Transmission routes are contact.[2]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Xipapillomavirus Bovines Epithelial: mucous; epithelial: skin Cell receptor endocytosis Lysis Nucleus Nucleus Contact

References[edit]

  1. ^ Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTv Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
  2. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  3. ^ a b "ICTV Report Papillomaviridae".

External links[edit]