Bemegride

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Bemegride
Bemegride.svg
Systematic (IUPAC) name
4-ethyl-4-methylpiperidine-2,6-dione
Clinical data
AHFS/Drugs.com International Drug Names
Legal status Prescription Only (S4) (AU)
Identifiers
CAS number 64-65-3 YesY
ATC code R07AB05
PubChem CID 2310
ChemSpider 2220 YesY
UNII 57DQA39DO2 YesY
KEGG D01957 YesY
ChEMBL CHEMBL1214192 YesY
Synonyms Methetharimide
β,β-methylethylglutarimide
Chemical data
Formula C8H13NO2 
Mol. mass 155.194 g/mol
 YesY (what is this?)  (verify)

Bemegride (also marketed as Megimide) is a central nervous system stimulant and antidote for barbiturate poisoning.

John Bodkin Adams case[edit]

Bemegride is notable in legal history as the drug suspected serial killer Dr John Bodkin Adams failed to prescribe correctly to his patient Gertrude Hullett. Hullett took an overdose of barbiturates on 19 July 1956 but Adams only gave her a single 10cc dose of bemegride three days later on the 22nd, despite having acquired 100cc for her treatment. Hullett died the next day on 23 July 1956. Adams was charged but never tried for her murder.[1]

Animal use[edit]

Bemegride is also used to induce convulsions in experimental animals.[2]

References[edit]

  1. ^ Cullen, Pamela V., A Stranger in Blood: The Case Files on Dr John Bodkin Adams, London, Elliott & Thompson, 2006, ISBN 1-904027-19-9
  2. ^ Definition: bemegride from Online Medical Dictionary