|Trade names||Enavid, Enovid|
The first combined oral contraceptive pill (COCP) was the combination mestranol and norethynodrel (INNs), sold as Enovid in the United States and as Enavid (in the United Kingdom). Developed by G. D. Searle & Company, it was first approved on June 10, 1957 by the U.S. Food and Drug Administration for treatment of menstrual disorders. The FDA approved an addidtional indication for use as a contraceptive on June 23, 1960. In 1961, it was approved as a contraceptive in the UK.
- "FDA Approved Drug Products". FDA.
- Junod, S. W.; Marks, L (2002). "Women's trials: the approval of the first oral contraceptive pill in the United States and Great Britain" (PDF). Journal of the History of Medicine and Allied Sciences 57 (2): 117–60. doi:10.1093/jhmas/57.2.117. PMID 11995593.
- "ANNOTATIONS". Br Med J 2 (5258): 1007–9. October 14, 1961. doi:10.1136/bmj.2.3490.1009. PMC 1970146. PMID 20789252.
- "Medical News". Br Med J 2 (5258): 1032. 1961 October 14. doi:10.1136/bmj.2.5258.1032. PMC 1970195.
- Reuters News Service (1988-04-15). "Searle, 2 others to stop making high-estrogen pill". St. Louis Post-Dispatch. pp. 7D. Retrieved 2009-08-29.
- "High-estrogen 'pill' going off market". San Jose Mercury News. 1988-04-15. Retrieved 2009-08-29.
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