Psychomotor agitation is a series of unintentional and purposeless motions that stem from mental tension and anxiety of an individual. This includes pacing around a room, wringing one's hands, pulling off clothing and putting it back on and other similar actions. In more severe cases, the motions may become harmful to the individual, such as ripping, tearing or chewing at the skin around one's fingernails or lips to the point of bleeding. Psychomotor agitation is a symptom typically found in major depressive disorder or obsessive-compulsive disorder, and sometimes the manic phase in bipolar disorder, although it can also be a result of an excess intake of stimulants. The middle aged and the elderly are more at risk to express this condition.
Both intramuscular midazolam and droperidol decrease the duration of agitation.
See also 
- ^ Isbister GK, Calver LA, Page CB, Stokes B, Bryant JL, Downes MA (October 2010). "Randomized controlled trial of intramuscular droperidol versus midazolam for violence and acute behavioral disturbance: the DORM study". Ann Emerg Med 56 (4): 392–401.e1. doi:10.1016/j.annemergmed.2010.05.037. PMID 20868907.