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Michael N. Hall

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Michael N. Hall
Michael N. Hall (2014)
NationalitySwiss, American
Alma materUniversity of North Carolina at Chapel Hill (B.S., 1976)
Harvard University (Ph.D., 1981)
Known formTOR
Awards

AND MORE

Scientific career
FieldsMolecular biology
InstitutionsUniversity of North Carolina at Chapel Hill
Harvard University
Institut Pasteur
University of California, San Francisco
Biozentrum University of Basel

Michael Nip Hall is an American and Swiss molecular biologist and Professor at the Biozentrum University of Basel, Switzerland.

Life

Hall grew up in South America (Venezuela, Peru). He earned a Bachelor of Science in Zoology from the University of North Carolina at Chapel Hill in 1976, and a PhD in Molecular Genetics from Harvard University in 1981. Hall was a postdoctoral fellow at the Institut Pasteur in Paris and at the University of California, San Francisco. He was appointed an Assistant Professor at the Biozentrum of the University of Basel in 1987, and became a Full Professor in 1992. From 1995 to 1998 and from 2002 to 2009 he was head of the Division of Biochemistry, and from 2002 until 2009 was Deputy Director of the Biozentrum.[1]

Work

Hall is a pioneer in the fields of TOR signaling and cell growth control.[2] In 1991, Michael N. Hall discovered a protein, which regulates cell growth, cell size and cell division in yeast cells.[3] Since the function of this protein is inhibited by the substance rapamycin, Hall gave the growth regulator the name «Target of Rapamycin» or for short «TOR». TOR is a conserved protein kinase activated by growth factors, nutrients, and insulin. It is a central controller of cell growth and metabolism. TOR plays a key role in aging and the development of diseases such as cancer, obesity, Diabetes mellitus, and cardiovascular disease. Insights into TOR signaling pathways have been applied for new therapeutic strategies.[4][5] In 2017, Hall received the Albert Lasker Basic Medical Research Award.[6]

Awards and honors

References

  1. ^ Curriculum Vitae Biozentrum.unibas.ch Retrieved 2013-10-22
  2. ^ Short Biography Archived 2014-10-18 at the Wayback Machine, De Duve Institute Retrieved 2013-10-22
  3. ^ "Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast". Science. 253: 905–9. Aug 1991. doi:10.1126/science.1715094. PMID 1715094.
  4. ^ Introduction Michael N. Hall Archived 2014-10-16 at the Wayback Machine bioss.uni-freiburg.de Retrieved 2013-10-22
  5. ^ Unveiling the Secret of Cell Growth Karger.com Retrieved 2015-09-16
  6. ^ Foundation, Lasker. "Nutrient-activated TOR proteins that regulate cell growth | The Lasker Foundation". The Lasker Foundation. Retrieved 2018-03-05.
  7. ^ European Molecular Biology Organization Membership Guide 2012 Retrieved 2013-10-22
  8. ^ Cloëtta Prize Website Retrieved 2013-10-22
  9. ^ Louis-Jeantet Prize
  10. ^ Marcel Benoist Prize 2012 marcel-benoist.ch Retrieved 2013-10-22
  11. ^ SAMS-Member Archived 2016-03-04 at the Wayback Machine samw.ch Retrieved 2013-10-22
  12. ^ Sir Hans Krebs Lecture Archived 2014-01-16 at the Wayback Machine FEBS-EMBO 2014 Retrieved 2013-10-22
  13. ^ First Breakthrough Prize in Life Sciences awarded to Swiss scientist. Archived 2013-12-14 at the Wayback Machine In: University of Basel, December 13, 2013
  14. ^ "Laureates: 2014". Breakthrough Prize in Life Sciences, Retrieved 2014-02-05. Archived from the original on 2014-01-06. Retrieved 2014-02-05.
  15. ^ "ERC Synergy Grant: EUR 11 million for Cancer Research" Archived 2013-12-19 at the Wayback Machine In: University of Basel, December 18, 2013
  16. ^ National Academy of Sciences Members and Foreign Associates Elected. Archived 2015-08-18 at the Wayback Machine nasonline.org Retrieved 2014-06-24
  17. ^ Michael N. Hall: Recipient of the Canada Gairdner International Award, 2015; Gairdner Foundation (gairdner.org); Retrieved 2015-03-31
  18. ^ Debrecen Award for Molecular Medicine 2016 Archived 2016-12-22 at the Wayback Machine; University of Debrecen (unideb.hu); Retrieved 2017-05-23
  19. ^ Doctor honoris causa, University of Geneva 2016; University of Geneva (unige.ch); Retrieved 2017-05-23
  20. ^ Szent-Györgyi Prize 2017 Archived 2017-02-15 at the Wayback Machine; National Foundation for Cancer (nfcr.org); Retrieved 2017-05-23
  21. ^ http://www.laskerfoundation.org/awards/year/2017/
  22. ^ http://www.brupbacher-foundation.org/en/research-prizes/brupbacher-prize/
  23. ^ http://medicine.uchicago.edu/events/106th-howard-taylor-ricketts-lecture-mtor-signaling-in-growth-and-metabolism/
  24. ^ https://www.hfsp.org/hfsp-nakasone-award/2019-michael-hall
  25. ^ Ansede, Manuel (2020-01-22). "Premio para los descubridores de un mecanismo para alargar la vida". El País (in Spanish). ISSN 1134-6582. Retrieved 2020-01-22.
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