Bilirubin-glucuronoside glucuronosyltransferase

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bilirubin-glucuronoside glucuronosyltransferase
Identifiers
EC number 2.4.1.95
CAS number 71822-22-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a bilirubin-glucuronoside glucuronosyltransferase (EC 2.4.1.95) is an enzyme that catalyzes the chemical reaction

2 bilirubin-glucuronoside bilirubin + bilirubin-bisglucuronoside

Hence, this enzyme has one substrate, bilirubin-glucuronoside, and two products, bilirubin and bilirubin-bisglucuronoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase. Other names in common use include bilirubin monoglucuronide transglucuronidase, and bilirubin glucuronoside glucuronosyltransferase.

References[edit]

  • Jansen PL, Chowdhury JR, Fischberg EB, Arias IM (1977). "Enzymatic conversion of bilirubin monoglucuronide to diglucuronide by rat liver plasma membranes". J. Biol. Chem. 252 (8): 2710–6. PMID 15996.