|Systematic (IUPAC) name|
|Oral, rectal, intravenous|
|Biological half-life||5 hours|
|Excretion||Renal (50%) and fecal|
|CAS Registry Number|
|Molecular mass||360.467 g/mol|
|(what is this?)|
Butylscopolamine is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring.
Hyoscine butylbromide is effective in significantly reducing the duration of the first stage of labour, and it is not associated with any obvious adverse outcomes in mother or neonate.
It is a quaternary ammonium compound and a semisynthetic derivative of scopolamine. The attachment of the butyl-bromide moiety effectively prevents the movement of this drug across the blood–brain barrier, effectively minimising undesirable central nervous system side effects associated with scopolamine/hyoscine.
Butylscopolamine is not centrally active and has a low incidence of abuse.
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