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Guanosine phosphorylase

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guanosine phosphorylase
Identifiers
EC no.2.4.2.15
CAS no.9030-28-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a guanosine phosphorylase (EC 2.4.2.15) is an enzyme that catalyzes the chemical reaction

guanosine + phosphate guanine + alpha-D-ribose 1-phosphate

Thus, the two substrates of this enzyme are guanosine and phosphate, whereas its two products are guanine and alpha-D-ribose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase. This enzyme participates in purine metabolism.

References

  • Yamada EW (1961). "The phosphorolysis of nucleosides by rabbit bone marrow". J. Biol. Chem. 236: 3043–3046. PMID 14008731.