Mannosylglycerate synthase
| Mannosylglycerate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.269 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with systematic name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- GDP-mannose + D-glycerate GDP + 2-O-(alpha-D-mannopyranosyl)-D-glycerate
Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate.
See also
- EC 2.4.1.217 (mannosyl-3-phosphoglycerate synthase)
- EC 3.1.3.70 (mannosyl-3-phosphoglycerate phosphatase)
References
- ^ Martins, L.O.; Empadinhas, N.; Marugg, J.D.; Miguel, C.; Ferreira, C.; da Costa, M.S.; Santos, H. (1999). "Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase". J. Biol. Chem. 274 (50): 35407–35414. doi:10.1074/jbc.274.50.35407. PMID 10585410.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Flint, J.; Taylor, E.; Yang, M.; Bolam, D.N.; Tailford, L.E.; Martinez-Fleites, C.; Dodson, E.J.; Davis, B.G.; Gilbert, H.J.; Davies, G.J. (2005). "Structural dissection and high-throughput screening of mannosylglycerate synthase". Nat. Struct. Mol. Biol. 12 (7): 608–614. doi:10.1038/nsmb950. PMID 15951819.
External links
- Mannosylglycerate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)