NCAPG2

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NCAPG2
Identifiers
AliasesNCAPG2, CAP-G2, CAPG2, LUZP5, MTB, hCAP-G2, non-SMC condensin II complex subunit G2
External IDsMGI: 1923294 HomoloGene: 9820 GeneCards: NCAPG2
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for NCAPG2
Genomic location for NCAPG2
Band7q36.3Start158,631,311 bp[1]
End158,704,829 bp[1]
RNA expression pattern
PBB GE NCAPG2 219588 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001281932
NM_001281933
NM_017760

NM_133762

RefSeq (protein)

NP_001268861
NP_001268862
NP_060230

NP_598523

Location (UCSC)Chr 7: 158.63 – 158.7 MbChr 12: 116.41 – 116.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Condensin-2 complex subunit G2 (CAP-G2) also known as chromosome-associated protein G2 (CAP-G2) or leucine zipper protein 5 (LUZP5) is a protein that in humans is encoded by the NCAPG2 gene.[5][6] CAP-G2 is a subunit of condensin II, a large protein complex involved in chromosome condensation. It interacts with PLK1 through its C-terminal region during mitosis[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146918 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042029 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (October 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–21. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.
  6. ^ "Entrez Gene: NCAPG2 non-SMC condensin II complex, subunit G2".
  7. ^ Kim JH, Shim J, Ji MJ, Jung Y, Bong SM, Jang YJ, Yoon EK, Lee SJ, Kim KG, Kim YH, Lee C, Lee BI, Kim KT (August 2014). "The condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores". Nature Communications. 5: 4588. doi:10.1038/ncomms5588. PMID 25109385.

Further reading[edit]