SMC2

From Wikipedia, the free encyclopedia
Jump to: navigation, search
SMC2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SMC2, CAP-E, CAPE, SMC-2, SMC2L1, structural maintenance of chromosomes 2
External IDs MGI: 106067 HomoloGene: 4705 GeneCards: SMC2
RNA expression pattern
PBB GE SMC2 213253 at fs.png

PBB GE SMC2 204240 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042550
NM_001042551
NM_001265602
NM_006444

NM_001301412
NM_008017

RefSeq (protein)

NP_001036015
NP_001036016
NP_001252531
NP_006435
NP_006435.2

NP_001288341.1
NP_032043.3
NP_001288341
NP_032043

Location (UCSC) Chr 9: 104.09 – 104.14 Mb Chr 4: 52.44 – 52.49 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Structural maintenance of chromosomes protein 2 (SMC-2) also known as chromosome-associated protein E (CAP-E) is a protein that in humans is encoded by the SMC2 gene.[3][4]

SMC-2 is a subunit of condensin I and II, large protein complexes involved in chromosome condensation.

Interactions[edit]

SMC2 has been shown to interact with DNMT3B.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Schmiesing JA, Ball AR, Gregson HC, Alderton JM, Zhou S, Yokomori K (Oct 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics". Proceedings of the National Academy of Sciences of the United States of America. 95 (22): 12906–11. doi:10.1073/pnas.95.22.12906. PMC 23650Freely accessible. PMID 9789013. 
  4. ^ "Entrez Gene: SMC2 structural maintenance of chromosomes 2". 
  5. ^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Research. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596Freely accessible. PMID 15148359. 

Further reading[edit]