Estradiol undecylate

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See also: estradiol and estrogen
Estradiol undecylate
Estradiol undecylate.svg
Systematic (IUPAC) name
(17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl undecanoate
Clinical data
Legal status Prescription only
Routes IM[1]
Identifiers
CAS number 3571-53-7
ATC code None
PubChem CID 19135
ChemSpider 18055
Synonyms 17β-Estradiol-17-undecanoate
Chemical data
Formula C29H44O3 
Mol. mass 440.658 g/mol

Estradiol undecylate (INN, USAN; brand names Delestrec, Depogin, Primogyn Depot, Progynon Depot, others) is a synthetic ester, specifically the 17-undecanoyl ester, of the natural estrogen, estradiol.[2][3] It has been in use since the mid-1950s,[4] and was formerly often used to treat prostate cancer, but has since largely been superseded by newer agents with fewer adverse effects for this indication.[1][5]

See also[edit]

References[edit]

  1. ^ a b Christoph Zink (1 January 1988). Dictionary of Obstetrics and Gynecology. Walter de Gruyter. p. 85. ISBN 978-3-11-085727-6. Retrieved 20 May 2012. 
  2. ^ A. D. Roberts (1991). Dictionary of Steroids: Chemical Data, Structures, and Bibliographies. CRC Press. p. 415. ISBN 978-0-412-27060-4. Retrieved 20 May 2012. 
  3. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 405. ISBN 978-3-88763-075-1. Retrieved 20 May 2012. 
  4. ^ WIED GL (January 1954). "[Estradiol valerate and estradiol undecylate, two new estrogens with prolonged action; comparison with estradiol benzoate]". Geburtshilfe Und Frauenheilkunde (in Undetermined) 14 (1): 45–52. PMID 13142295. 
  5. ^ Ernst Mutschler; Hartmut Derendorf (1995). Drug Actions: Basic Principles and Therapeutic Aspects. CRC Press. p. 609. ISBN 978-0-8493-7774-7. Retrieved 30 January 2013.