Tetrahydrocorticosterone

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Tetrahydrocorticosterone
Names
IUPAC name
3α,11β,21-Trihydroxy-5β-pregnan-20-one
Other names
3α,5α-Tetrahydrocorticosterone; 5β-Pregnane-3α,11β,21-triol-20-one
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.000.627 Edit this at Wikidata
  • InChI=1S/C21H34O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-17,19,22-24H,3-11H2,1-2H3/t12?,13?,14?,15-,16+,17?,19+,20-,21-/m0/s1
    Key: RHQQHZQUAMFINJ-WAWWIEPNSA-N
  • InChI=1/C21H34O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-17,19,22-24H,3-11H2,1-2H3/t12?,13?,14?,15-,16+,17?,19+,20-,21-/m0/s1
    Key: RHQQHZQUAMFINJ-WAWWIEPNBT
  • OCC(=O)[C@H]4CC[C@H]3C2CCC1CC(O)CC[C@]1(C)[C@H]2C(O)C[C@@]34C
Properties
C21H34O4
Molar mass 350.499 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

3α,5α-Tetrahydrocorticosterone (3α,5α-THB), or simply tetrahydrocorticosterone (THB or THCC), is an endogenous glucocorticoid hormone.[1]

See also

References

  1. ^ McInnes KJ, Kenyon CJ, Chapman KE, et al. (May 2004). "5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor". The Journal of Biological Chemistry. 279 (22): 22908–12. doi:10.1074/jbc.M402822200. PMID 15044432.