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Berefrine

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Berefrine
Clinical data
Other namesBurefrine; Phenylephrine oxazolidine; Phenylephrine oxazolidine prodrug
ATC code
  • None
Identifiers
  • 3-[(5R)-3-Methyl-2-(2-methyl-2-propanyl)-1,3-oxazolidin-5-yl]phenol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC14H21NO2
Molar mass235.327 g·mol−1
3D model (JSmol)
  • CC(C)(C)C1N(C[C@H](O1)c2cccc(c2)O)C
  • InChI=1S/C14H21NO2/c1-14(2,3)13-15(4)9-12(17-13)10-6-5-7-11(16)8-10/h5-8,12-13,16H,9H2,1-4H3/t12-,13?/m0/s1
  • Key:ORIOFGXXYYXLNY-UEWDXFNNSA-N

Berefrine (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name), also known as burefrine, is a sympathomimetic and mydriatic medication that was never marketed.[1][2] It is described as an oxazolidine prodrug of phenylephrine and hence would act as a selective α1-adrenergic receptor agonist.[3][better source needed]

See also

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References

[edit]
  1. ^ Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 615–. ISBN 978-0-412-46630-4.
  2. ^ World Health Organization (2000). International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization. ISBN 978-0-11-986227-0.
  3. ^ "3-(2-Tert-butyl-3-methyl-1,3-oxazolidin-5-yl)phenol". PubChem. Retrieved 31 August 2024.



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