Diethyl 3-quinolinyl phosphate
3D model (JSmol)
|Molar mass||281.248 g·mol−1|
|Main hazards||Highly toxic|
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|1 mg/kg (mice, intravenous)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It's the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, so it's able to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.
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